| 9/4/2010 | St Thomas 40 @ St Norbert Green Knights 7 | |
| 9/11/2010 | Wisconsin-River Falls Falcons 3 @ St Thomas 27 | |
| 9/18/2010 | St Thomas 49 @ St Olaf Oles 14 | † |
| 9/25/2010 | Concordia-Moorhead Cobbers 7 @ St Thomas 56 | † |
| 10/2/2010 | St Thomas 27 @ St John's MN Johnnies 26 | † |
| 10/9/2010 | Augsburg Auggies 17 @ St Thomas 55 | † |
| 10/16/2010 | St Thomas 61 @ Hamline Pipers 17 | † |
| 10/23/2010 | Bethel MN Royals 6 @ St Thomas 10 | † |
| 10/30/2010 | St Thomas 43 @ Gustavus Adolphus Golden Gusties 6 | † |
| 11/6/2010 | Carleton Knights 7 @ St Thomas 38 | † |
| 11/20/2010 | Ill. Benedictine Eagles 10 @ St Thomas 57 | |
| 11/27/2010 | Linfield Wildcats 17 @ St Thomas 24 2OT | |
| 12/4/2010 | Bethel MN Royals 12 @ St Thomas 7 | † |