Wofford Common Opponents (12)
11 Jan 2011 5:05pm (US Central)
| 0-1 | — | 0 | (1 Common Ops) | 0 | Akron | 1-11 |
| L 10-33 at | 9/4/2010 | Ohio (6-5) | 10/16/2010 | L 10-38 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Bowling Green | 2-10 |
| L 10-33 at | 9/4/2010 | Ohio (6-5) | 10/9/2010 | L 25-49 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Buffalo | 2-10 |
| L 10-33 at | 9/4/2010 | Ohio (6-5) | 11/4/2010 | L 17-34 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Eastern Michigan | 2-10 |
| L 10-33 at | 9/4/2010 | Ohio (6-5) | 10/2/2010 | L 17-30 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Kent State | 5-7 |
| L 10-33 at | 9/4/2010 | Ohio (7-4) | 11/26/2010 | W 28-6 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Marshall | 5-7 |
| L 10-33 at | 9/4/2010 | Ohio (7-4) | 9/25/2010 | W 24-23 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Miami-Ohio | 10-4 |
| L 10-33 at | 9/4/2010 | Ohio (6-5) | 10/23/2010 | L 13-34 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Ohio State | 12-1 |
| L 10-33 at | 9/4/2010 | Ohio (7-4) | 9/18/2010 | W 43-7 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Temple | 8-4 |
| L 10-33 at | 9/4/2010 | Ohio (6-5) | 11/16/2010 | L 23-31 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Toledo | 8-5 |
| L 10-33 at | 9/4/2010 | Ohio (7-4) | 9/11/2010 | W 20-13 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Troy | 8-5 |
| L 10-33 at | 9/4/2010 | Ohio (7-4) | 12/18/2010 | W 48-21 vs |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | UL Lafayette | 3-9 |
| L 10-33 at | 9/4/2010 | Ohio (6-5) | 10/30/2010 | L 31-38 at |
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