11 Jan 2011 5:05pm (US Central)
| 0-1 | — | 0 | (1 Common Ops) | 0 | Baylor | 7-6 |
| L 3-35 at | 9/11/2010 | Illinois (5-6) | 12/29/2010 | L 14-38 vs |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Fresno State | 8-5 |
| L 3-35 at | 9/11/2010 | Illinois (6-5) | 12/3/2010 | W 25-23 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Indiana | 5-7 |
| L 3-35 at | 9/11/2010 | Illinois (5-6) | 10/23/2010 | L 13-43 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Michigan | 7-6 |
| L 3-35 at | 9/11/2010 | Illinois (6-5) | 11/6/2010 | W 67-65 3 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Michigan State | 11-2 |
| L 3-35 at | 9/11/2010 | Illinois (6-5) | 10/16/2010 | W 26-6 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Minnesota | 3-9 |
| L 3-35 at | 9/11/2010 | Illinois (6-5) | 11/13/2010 | W 38-34 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Missouri | 10-3 |
| L 3-35 at | 9/11/2010 | Illinois (6-5) | 9/4/2010 | W 23-13 vs |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Northern Illinois | 11-3 |
| L 3-35 at | 9/11/2010 | Illinois (5-6) | 9/18/2010 | L 22-28 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Northwestern | 7-6 |
| L 3-35 at | 9/11/2010 | Illinois (5-6) | 11/20/2010 | L 27-48 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Ohio State | 12-1 |
| L 3-35 at | 9/11/2010 | Illinois (6-5) | 10/2/2010 | W 24-13 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Penn State | 7-6 |
| L 3-35 at | 9/11/2010 | Illinois (5-6) | 10/9/2010 | L 13-33 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Purdue | 4-8 |
| L 3-35 at | 9/11/2010 | Illinois (5-6) | 10/30/2010 | L 10-44 at |
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