11 Jan 2011 5:05pm (US Central)
| 0-1 | — | 0 | (1 Common Ops) | 0 | Akron | 1-11 |
| L 10-27 at | 9/2/2010 | Ball State (2-8) | 11/6/2010 | L 30-37 2 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Buffalo | 2-10 |
| L 10-27 at | 9/2/2010 | Ball State (2-8) | 11/12/2010 | L 3-20 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Central Michigan | 3-9 |
| L 10-27 at | 9/2/2010 | Ball State (2-8) | 10/2/2010 | L 17-31 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Eastern Michigan | 2-10 |
| L 10-27 at | 9/2/2010 | Ball State (3-7) | 10/16/2010 | W 41-38 1 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Iowa | 8-5 |
| L 10-27 at | 9/2/2010 | Ball State (3-7) | 9/25/2010 | W 45-0 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Kent State | 5-7 |
| L 10-27 at | 9/2/2010 | Ball State (3-7) | 10/30/2010 | W 33-14 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Liberty | 1-0 |
| L 10-27 at | 9/2/2010 | Ball State (3-7) | 9/11/2010 | W 27-23 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Northern Illinois | 11-3 |
| L 10-27 at | 9/2/2010 | Ball State (3-7) | 11/20/2010 | W 59-21 at |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Purdue | 4-8 |
| L 10-27 at | 9/2/2010 | Ball State (3-7) | 9/18/2010 | W 24-13 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Toledo | 8-5 |
| L 10-27 at | 9/2/2010 | Ball State (3-7) | 10/23/2010 | W 31-24 |
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| 0-1 | — | 0 | (1 Common Ops) | 0 | Western Michigan | 6-6 |
| L 10-27 at | 9/2/2010 | Ball State (3-7) | 10/9/2010 | W 45-16 at |
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