11 Jan 2011 5:04pm (US Central)
| 1-0 | — | 0 | (1 Common Ops) | 0 | Boise State | 12-1 |
| W 21-16 at | 9/11/2010 | Virginia Tech (11-1) | 9/6/2010 | W 33-30 vs |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Boston College | 7-6 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 9/25/2010 | L 0-19 |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Central Michigan | 3-9 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 10/9/2010 | L 21-45 at |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Duke | 3-9 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 10/23/2010 | L 7-44 at |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | East Carolina | 6-7 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 9/18/2010 | L 27-49 at |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Florida State | 10-4 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 12/4/2010 | L 33-44 vs |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Georgia Tech | 6-7 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 11/4/2010 | L 21-28 at |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Miami-Florida | 7-6 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 11/20/2010 | L 17-31 |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | North Carolina | 8-5 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 11/13/2010 | L 10-26 |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | North Carolina State | 9-4 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 10/2/2010 | L 30-41 |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Stanford | 12-1 |
| W 21-16 at | 9/11/2010 | Virginia Tech (11-1) | 1/3/2011 | W 40-12 vs |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Virginia | 4-8 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 11/27/2010 | L 7-37 at |
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| 1-0 | — | 0 | (1 Common Ops) | 0 | Wake Forest | 3-9 |
| W 21-16 at | 9/11/2010 | Virginia Tech (10-2) | 10/16/2010 | L 21-52 at |
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