| Date | Visitor | Typ | Home | Location, If neutral |
| 2-Sep | Southern California | at | Hawaii |
| 2-Sep | Northern Illinois | at | Iowa State |
| 2-Sep | Minnesota | at | Middle Tenn St |
| 2-Sep | Marshall | at | Ohio State |
| 2-Sep | Southern Miss | at | South Carolina |
| 2-Sep | Pittsburgh | at | Utah |
| 3-Sep | Arizona | at | Toledo |
| 4-Sep | Syracuse | at | Akron |
| 4-Sep | San Jose St | at | Alabama |
| 4-Sep | Arkansas St | at | Auburn |
| 4-Sep | Washington | at | BYU |
| 4-Sep | North Texas | at | Clemson |
| 4-Sep | Colorado St | vs | Colorado | Denver CO |
| 4-Sep | Miami-Ohio | at | Florida |
| 4-Sep | Cincinnati | at | Fresno St |
| 4-Sep | UL Lafayette | at | Georgia |
| 4-Sep | Louisiana Tech | vs | Grambling | Shreveport LA |
| 4-Sep | Western Michigan | at | Michigan St |
| 4-Sep | Memphis | at | Mississippi St |
| 4-Sep | Western Kentucky | at | Nebraska |
| 4-Sep | Utah St | at | Oklahoma |
| 4-Sep | New Mexico | at | Oregon |
| 4-Sep | Texas | at | Rice |
| 4-Sep | Oregon St | vs | TCU | Arlington TX |
| 4-Sep | Wisconsin | at | UNLV |
| 5-Sep | SMU | at | Texas Tech |
| 6-Sep | Maryland | vs | Navy | Baltimore MD |
| 6-Sep | Boise St | vs | Virginia Tech | Landover MD |
| 10-Sep | West Virginia | at | Marshall |
| 11-Sep | UL Monroe | vs | Arkansas | Little Rock AR |
| 11-Sep | Buffalo | at | Baylor |
| 11-Sep | Kent St | at | Boston College |
| 11-Sep | Rutgers | at | Florida Intl |
| 11-Sep | Western Kentucky | at | Kentucky |
| 11-Sep | Florida Atlantic | vs | Michigan St | Detroit MI |
| 11-Sep | Idaho | at | Nebraska |
| 11-Sep | Texas Tech | at | New Mexico |
| 11-Sep | Troy | at | Oklahoma St |
| 11-Sep | Wyoming | at | Texas |
| 11-Sep | Louisiana Tech | at | Texas A&M |
| 11-Sep | Mississippi | at | Tulane |
| 11-Sep | North Carolina St | at | UCF |
| 11-Sep | San Jose St | at | Wisconsin |
| 17-Sep | California | at | Nevada |
| 17-Sep | Kansas | at | Southern Miss |
| 18-Sep | Hawaii | at | Colorado |
| 18-Sep | BYU | at | Florida St |
| 18-Sep | Northern Illinois | at | Illinois |
| 18-Sep | Akron | at | Kentucky |
| 18-Sep | San Diego St | at | Missouri |
| 18-Sep | Ohio | at | Ohio State |
| 18-Sep | Air Force | at | Oklahoma |
| 18-Sep | Tulsa | at | Oklahoma St |
| 18-Sep | Kent St | at | Penn State |
| 18-Sep | Ball State | at | Purdue |
| 18-Sep | Northwestern | at | Rice |
| 18-Sep | Washington St | at | SMU |
| 18-Sep | Baylor | at | TCU |
| 18-Sep | Connecticut | at | Temple |
| 18-Sep | Florida Intl | at | Texas A&M |
| 18-Sep | Houston | at | UCLA |
| 18-Sep | East Carolina | at | Virginia Tech |
| 18-Sep | Indiana | at | Western Kentucky |
| 25-Sep | Oregon St | at | Boise St |
| 25-Sep | Buffalo | at | Connecticut |
| 25-Sep | Army | at | Duke |
| 25-Sep | Akron | at | Indiana |
| 25-Sep | Ball State | at | Iowa |
| 25-Sep | New Mexico St | at | Kansas |
| 25-Sep | UCF | at | Kansas St |
| 25-Sep | Florida Intl | at | Maryland |
| 25-Sep | Bowling Green | at | Michigan |
| 25-Sep | Northern Illinois | at | Minnesota |
| 25-Sep | Fresno St | at | Mississippi |
| 25-Sep | Miami-Ohio | at | Missouri |
| 25-Sep | Central Michigan | at | Northwestern |
| 25-Sep | Eastern Michigan | at | Ohio State |
| 25-Sep | Temple | at | Penn State |
| 25-Sep | Toledo | at | Purdue |
| 25-Sep | Baylor | at | Rice |
| 25-Sep | Western Kentucky | at | South Florida |
| 25-Sep | UAB | at | Tennessee |
| 2-Oct | Louisville | at | Arkansas St |
| 2-Oct | UL Monroe | at | Auburn |
| 2-Oct | East Carolina | at | North Carolina |
| 2-Oct | Florida Intl | at | Pittsburgh |
| 2-Oct | Tulane | at | Rutgers |
| 2-Oct | Florida Atlantic | at | South Florida |
| 8-Oct | Oklahoma St | at | UL Lafayette |
| 9-Oct | Miami-Ohio | at | Cincinnati |
| 9-Oct | Mississippi St | at | Houston |
| 9-Oct | Utah | at | Iowa State |
| 9-Oct | Memphis | at | Louisville |
| 9-Oct | Eastern Michigan | at | Vanderbilt |
| 9-Oct | Central Michigan | at | Virginia Tech |
| 9-Oct | Navy | at | Wake Forest |
| 9-Oct | UNLV | at | West Virginia |
| 16-Oct | North Carolina St | at | East Carolina |
| 16-Oct | Middle Tenn St | at | Georgia Tech |
| 16-Oct | Arkansas St | at | Indiana |
| 16-Oct | Western Michigan | at | Notre Dame |
| 16-Oct | Army | at | Rutgers |
| 23-Oct | UAB | at | Mississippi St |
| 23-Oct | Notre Dame | vs | Navy | East Rutherford NJ |
| 23-Oct | Eastern Michigan | at | Virginia |
| 30-Oct | Duke | at | Navy |
| 30-Oct | Tulsa | at | Notre Dame |
| 6-Nov | Tennessee | at | Memphis |
| 6-Nov | UL Lafayette | at | Mississippi |
| 13-Nov | UTEP | at | Arkansas |
| 13-Nov | UL Monroe | at | LSU |
| 13-Nov | Utah | at | Notre Dame |
| 20-Nov | Notre Dame | vs | Army | Bronx NY |
| 20-Nov | Troy | at | South Carolina |
| 20-Nov | Florida Atlantic | at | Texas |
| 27-Nov | Kansas St | at | North Texas |
| 27-Nov | Houston | at | Texas Tech |
| 3-Dec | Illinois | at | Fresno St |
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