| 9/5/2009 | Birmingham-Southern 27 @ LaGrange 30 | |
| 9/12/2009 | LaGrange 19 @ Shorter 42 | |
| 9/19/2009 | Maryville 23 @ LaGrange 6 | |
| 9/26/2009 | Wesley 56 @ LaGrange 7 | |
| 10/3/2009 | LaGrange 20 @ Lincoln MO 7 | |
| 10/10/2009 | MacMurray 6 @ LaGrange 48 | |
| 10/17/2009 | LaGrange 37 @ Eureka 10 | |
| 10/24/2009 | Westminster MO 17 @ LaGrange 34 | |
| 10/31/2009 | LaGrange 13 @ Huntingdon AL 51 | † |
| 11/14/2009 | LaGrange 21 @ Greenville 28 |