| 9/5/2009 | Western Kentucky 7 @ Tennessee 63 | |
| 9/12/2009 | South Florida 35 @ Western Kentucky 13 | |
| 9/19/2009 | Central Arkansas 28 @ Western Kentucky 7 | |
| 9/26/2009 | Western Kentucky 22 @ Navy 38 | |
| 10/10/2009 | Florida Intl 37 @ Western Kentucky 20 | † |
| 10/17/2009 | UL Lafayette 30 @ Western Kentucky 22 | † |
| 10/24/2009 | Western Kentucky 24 @ Middle Tenn St 62 | † |
| 10/31/2009 | Western Kentucky 49 @ North Texas 68 | † |
| 11/7/2009 | Troy 40 @ Western Kentucky 20 | † |
| 11/14/2009 | Western Kentucky 18 @ UL Monroe 21 | † |
| 11/28/2009 | Western Kentucky 23 @ Florida Atlantic 29 | † |
| 12/3/2009 | Arkansas St 24 @ Western Kentucky 20 | † |