| 9/5/2009 | North Carolina Central | 24 | @ | Hampton | 31 | ||||
| 9/12/2009 | Hampton | 24 | @ | Alabama A&M | 31 | ||||
| 9/19/2009 | Hampton | 24 | @ | NC A&T | 14 | MEAC | |||
| 9/26/2009 | Delaware St | 21 | @ | Hampton | 6 | MEAC | |||
| 10/10/2009 | Howard | 0 | @ | Hampton | 37 | MEAC | |||
| 10/17/2009 | Hampton | 6 | @ | Norfolk St | 46 | MEAC | |||
| 10/24/2009 | S Carolina St | 21 | @ | Hampton | 9 | MEAC | |||
| 10/31/2009 | Hampton | 16 | @ | Winston-Salem St | 13 | OT | MEAC | ||
| 11/7/2009 | Hampton | 24 | @ | Bethune-Cookman | 27 | MEAC | |||
| 11/14/2009 | Florida A&M | 0 | @ | Hampton | 25 | MEAC | |||
| 11/21/2009 | Morgan St | 16 | @ | Hampton | 13 | MEAC |