| Thursday, 9 Oct 2008 |
| MEAC | Winston-Salem St | 0 | @ | Florida A&M | 23 | | |
| Kentucky Christian (NAIA) | 33 | @ | Georgetown KY (NAIA) | 58 | | |
| CUSA | Alabama-Birmingham | 20 | @ | Houston | 45 | | |
| Webber Int'l (NAIA) | 7 | @ | Jacksonville FL | 51 | | |
| North Alabama (D2) | 52 | @ | North Greenville (D2) | 7 | | |
| OVC | Eastern Illinois | 26 | @ | Tennessee-Martin | 29 | | |
| ACC | Clemson | 7 | @ | #23 Wake Forest | 12 | | |
| Friday, 10 Oct 2008 |
| Cen | Dickinson (D3) | 34 | @ | Johns Hopkins (D3) | 36 | | |
| Louisville | 35 | @ | Memphis | 28 | | |
| NE10 | St Anselm (D2) | 48 | @ | Merrimack (D2) | 42 | | |
| NE10 | Bentley (D2) | 14 | @ | Southern Conn St (D2) | 47 | | |
| D3Ind | Gallaudet (D3) | 0 | @ | SUNY-Maritime (D3) | 27 | | |
| Saturday, 11 Oct 2008 |
| LSC | Angelo St (D2) (3-3) | | @ | Abilene Christian (D2) (5-0) | | | |
| RMAC | Fort Lewis (D2) (2-4) | | @ | Adams St (D2) (1-5) | | | |
| MAC | Bowling Green (2-3) | | @ | Akron (3-3) | | | |
| SWAC | Grambling St (3-3) | | @ | Alabama A&M (2-4) | | | |
| NE | Central Conn St (4-1) | | @ | Albany NY (2-3) | | | |
| SIAC | Clark Atlanta (D2) (4-2) | | @ | Albany St GA (D2) (4-1) | | | |
| MIAA | Hope (D3) (0-5) | | @ | Albion (D3) (2-3) | | | |
| Carnegie Mellon (D3) (3-2) | | @ | Allegheny (D3) (2-2) | | | |
| NE10 | Stonehill (D2) (1-4) | | @ | American Int'l (D2) (5-0) | | | |
| NESCAA | Colby (D3) (2-1) | | @ | Amherst (D3) (2-1) | | | |
| SBC | Louisiana-Monroe (1-4) | | @ | Arkansas St (3-2) | | | |
| GSC | West Georgia (D2) (0-5) | | @ | Arkansas-Monticello (D2) (4-2) | | | |
| SWAC | Jackson St (1-4) | | @ | Arkansas-Pine Bluff (0-5) | | | |
| Eastern Michigan (2-4) | | @ | Army (1-4) | | | |
| NE10 | Pace (D2) (3-2) | | @ | Assumption (D2) (1-4) | | | |
| SEC | Arkansas (2-3) | | @ | Auburn (4-2) | | | |
| CCIW | Wheaton (D3) (4-0) | | @ | Augustana IL (D3) (3-1) | | | |
| SW Minnesota St (D2) (3-3) | | @ | Augustana SD (D2) (4-2) | | | |
| Sewanee (D3) (2-3) | | @ | Austin (D3) (2-3) | | | |
| NESCAA | Wesleyan (D3) (0-3) | | @ | Bates (D3) (0-3) | | | |
| B12 | Iowa St (2-3) | | @ | Baylor (2-3) | | | |
| West Virginia Tech (D2) (0-5) | | @ | Belhaven (NAIA) (1-4) | | | |
| IBC | Concordia WI (D3) (1-3) | | @ | Benedictine IL (D3) (0-4) | | | |
| HAAC | Lindenwood (NAIA) (3-1) | | @ | Benedictine KS (NAIA) (2-3) | | | |
| KCAC | Tabor (NAIA) (0-4) | | @ | Bethany KS (NAIA) (0-4) | | | |
| MIA | St Olaf (D3) (3-2) | | @ | Bethel MN (D3) (2-3) | | | |
| MEAC | Delaware St (1-3) | | @ | Bethune-Cookman (4-1) | | | |
| DAC | Valley City St (NAIA) (2-3) | | @ | Black Hills St (NAIA) (4-1) | | | |
| UMWAC | Principia (D3) (0-4) | | @ | Blackburn (D3) (1-5) | | | |
| PSAC | East Stroudsburg (D2) (5-1) | | @ | Bloomsburg (D2) (6-0) | | | |
| CIAA | Elizabeth City St (D2) (3-3) | | @ | Bowie St (D2) (3-2) | | | |
| MW | New Mexico (3-3) | | @ | #21 Brigham Young (5-0) | | | |
| New Jersey (D3) (2-2) | | @ | Brockport St (D3) (1-3) | | | |
| Hofstra (2-3) | | @ | Bucknell (3-1) | | | |
| MAC | Western Michigan (5-1) | | @ | Buffalo (2-3) | | | |
| Kean (D3) (3-1) | | @ | Buffalo St (D3) (0-4) | | | |
| SCIAC | Pomona-Pitzer (D3) (1-2) | | @ | Cal Lutheran (D3) (2-1) | | | |
| PSAC | Lock Haven (D2) (0-6) | | @ | California PA (D2) (5-1) | | | |
| Pio | Butler (3-1) | | @ | Campbell (1-5) | | | |
| MIA | Augsburg (D3) (4-0) | | @ | Carleton (D3) (4-0) | | | |
| Front | Montana-Western (NAIA) (2-4) | | @ | Carroll MT (NAIA) (6-0) | | | |
| CCIW | Elmhurst (D3) (3-1) | | @ | Carthage (D3) (3-1) | | | |
| Wooster (D3) (4-0) | | @ | Case Western Reserve (D3) (4-0) | | | |
| SAC | Carson-Newman (D2) (3-2) | | @ | Catawba (D2) (3-2) | | | |
| ODC | Washington and Lee (D3) (4-1) | | @ | Catholic (D3) (4-1) | | | |
| SLC | Sam Houston St (2-1) | | @ | Central Arkansas (4-1) | | | |
| IIAC | Dubuque (D3) (1-3) | | @ | Central IA (D3) (2-2) | | | |
| HAAC | MidAmerica Nazarene (NAIA) (5-0) | | @ | Central Methodist (NAIA) (1-4) | | | |
| MAC | Temple (2-4) | | @ | Central Michigan (3-2) | | | |
| MAIAA | NW Missouri St (D2) (5-1) | | @ | Central Missouri (D2) (5-1) | | | |
| LSC | SE Oklahoma St (D2) (2-4) | | @ | Central Oklahoma (D2) (2-4) | | | |
| Langston (D2) (3-2) | | @ | Central St OH (D2) (0-5) | | | |
| SCAC | Millsaps (D3) (5-0) | | @ | Centre (D3) (3-2) | | | |
| RMAC | Western New Mexico (D2) (0-5) | | @ | Chadron St (D2) (5-1) | | | |
| WVIAC | Fairmont St (D2) (3-3) | | @ | Charleston WV (D2) (4-2) | | | |
| Oberlin (D3) (1-3) | | @ | Chicago (D3) (0-3) | | | |
| Livingstone (D2) (2-4) | | @ | Chowan (D2) (1-5) | | | |
| USASC | Greensboro (D3) (2-2) | | @ | Christopher Newport (D3) (2-1) | | | |
| BigE | Rutgers (1-4) | | @ | Cincinnati (4-1) | | | |
| SCIAC | La Verne (D3) (0-3) | | @ | Claremont-Mudd-Scripps (D3) (1-2) | | | |
| PSAC | Slippery Rock (D2) (3-3) | | @ | Clarion (D2) (1-5) | | | |
| IIAC | Wartburg (D3) (3-2) | | @ | Coe (D3) (2-3) | | | |
| Princeton (2-1) | | @ | Colgate (3-2) | | | |
| MW | #22 TCU (5-1) | | @ | Colorado St (3-2) | | | |
| Lafayette (3-1) | | @ | Columbia (0-3) | | | |
| Miles (D2) (1-4) | | @ | Concordia AL (NAIA) (3-3) | | | |
| MIA | St Thomas (D3) (3-1) | | @ | Concordia-Moorhead (D3) (3-1) | | | |
| IIAC | Simpson (D3) (3-2) | | @ | Cornell IA (D3) (0-5) | | | |
| NJAC | Montclair St (D3) (4-0) | | @ | Cortland St (D3) (4-0) | | | |
| UMWAC | Minnesota-Morris (NAIA) (2-2) | | @ | Crown (NAIA) (2-3) | | | |
| NEF | MIT (D3) (3-2) | | @ | Curry (D3) (5-0) | | | |
| DAC | Minot St (NAIA) (2-3) | | @ | Dakota St (NAIA) (2-3) | | | |
| GPAC | Doane (NAIA) (2-3) | | @ | Dakota Wesleyan (NAIA) (3-2) | | | |
| Ivy | Yale (2-1) | | @ | Dartmouth (0-3) | | | |
| Pio | Drake (2-3) | | @ | Dayton (4-1) | | | |
| CAAF | Maine (2-3) | | @ | Delaware (2-3) | | | |
| MidAC | Lebanon Valley (D3) (3-1) | | @ | Delaware Valley (D3) (3-1) | | | |
| GSC | West Alabama (D2) (3-3) | | @ | Delta St (D2) (4-1) | | | |
| SCAC | Birmingham-Southern (D3) (1-3) | | @ | DePauw (D3) (3-1) | | | |
| D2Ind | Humboldt St (D2) (2-4) | | @ | Dixie St (D2) (1-5) | | | |
| GPAC | Concordia NE (NAIA) (1-4) | | @ | Dordt (NAIA) (0-5) | | | |
| OVC | Jacksonville St (4-1) | | @ | Eastern Kentucky (3-3) | | | |
| LSC | West Texas A&M (D2) (6-0) | | @ | Eastern New Mexico (D2) (1-5) | | | |
| BSky | Montana (4-1) | | @ | Eastern Washington (1-3) | | | |
| PSAC | Indiana PA (D2) (4-1) | | @ | Edinboro (D2) (5-1) | | | |
| Plymouth St (D3) (4-1) | | @ | Endicott (D3) (2-3) | | | |
| Huntingdon (D3) (4-0) | | @ | Eureka (D3) (2-2) | | | |
| HAAC | Avila (NAIA) (2-3) | | @ | Evangel (NAIA) (2-3) | | | |
| Cumberland TN (NAIA) (2-3) | | @ | Faulkner (NAIA) (0-5) | | | |
| MidAC | Wilkes (D3) (0-4) | | @ | FDU-Florham (D3) (2-2) | | | |
| Maryville (D3) (3-2) | | @ | Ferrum (D3) (4-1) | | | |
| GLIAC | Michigan Tech (D2) (4-2) | | @ | Findlay (D2) (2-4) | | | |
| Coast Guard (D3) (2-2) | | @ | Fitchburg St (D3) (1-4) | | | |
| SEC | #20 LSU (4-0) | | @ | #16 Florida (4-1) | | | |
| SBC | Middle Tennessee St (2-3) | | @ | Florida Int'l (2-3) | | | |
| Missouri Southern (D2) (3-3) | | @ | Fort Hays St (D2) (2-4) | | | |
| NEF | Bridgewater St MA (D3) (2-3) | | @ | Framingham St (D3) (3-2) | | | |
| HCA | Bluffton (D3) (1-3) | | @ | Franklin (D3) (3-1) | | | |
| Cen | Ursinus (D3) (2-2) | | @ | Franklin & Marshall (D3) (2-2) | | | |
| WAC | Idaho (1-5) | | @ | Fresno St (3-2) | | | |
| SW Assem of God (NAIA) (1-3) | | @ | Friends (NAIA) (4-0) | | | |
| SoCon | Western Carolina (2-4) | | @ | Furman (4-2) | | | |
| GLIAC | Mercyhurst (D2) (4-2) | | @ | Gannon (D2) (3-3) | | | |
| Pennsylvania (1-2) | | @ | Georgetown DC (1-3) | | | |
| SEC | Tennessee (2-3) | | @ | #12 Georgia (4-1) | | | |
| Gardner-Webb (2-3) | | @ | #19 Georgia Tech (4-1) | | | |
| Moravian (D3) (4-1) | | @ | Gettysburg (D3) (1-4) | | | |
| HAAC | Culver-Stockton (NAIA) (0-5) | | @ | Graceland (NAIA) (0-5) | | | |
| GLIAC | Hillsdale (D2) (4-2) | | @ | Grand Valley St (D2) (5-0) | | | |
| MidW | Knox (D3) (1-4) | | @ | Grinnell (D3) (2-3) | | | |
| Geneva (NAIA) (1-3) | | @ | Grove City (D3) (3-2) | | | |
| NESCAA | Bowdoin (D3) (1-2) | | @ | Hamilton (D3) (1-2) | | | |
| ODC | Emory & Henry (D3) (2-2) | | @ | Hampden-Sydney (D3) (5-0) | | | |
| Rose-Hulman (D3) (4-1) | | @ | Hanover (D3) (0-3) | | | |
| GSC | Ouachita Baptist (D2) (2-3) | | @ | Harding (D2) (2-4) | | | |
| ASWC | East Texas Baptist (D3) (3-1) | | @ | Hardin-Simmons (D3) (4-1) | | | |
| E8 | Alfred (D3) (4-1) | | @ | Hartwick (D3) (2-1) | | | |
| Ivy | Cornell NY (3-0) | | @ | Harvard (2-1) | | | |
| WAC | Louisiana Tech (2-2) | | @ | Hawaii (2-3) | | | |
| OAC | Ohio Northern (D3) (0-4) | | @ | Heidelberg (D3) (1-3) | | | |
| GSC | Valdosta St (D2) (3-1) | | @ | Henderson St (D2) (3-3) | | | |
| NCA | Denison (D3) (1-3) | | @ | Hiram (D3) (2-2) | | | |
| LL | Union NY (D3) (1-3) | | @ | Hobart (D3) (4-0) | | | |
| Brown (2-1) | | @ | Holy Cross (1-3) | | | |
| Springfield (D3) (1-3) | | @ | Husson (D3) (3-2) | | | |
| B10 | Minnesota (5-1) | | @ | Illinois (3-2) | | | |
| MidW | Carroll WI (D3) (3-2) | | @ | Illinois College (D3) (2-3) | | | |
| B10 | Iowa (3-3) | | @ | Indiana (2-3) | | | |
| GLIAC | Ferris St (D2) (4-2) | | @ | Indianapolis (D2) (3-3) | | | |
| Wesley (D3) (2-1) | | @ | Iona (3-2) | | | |
| CIAA | St Augustine's (D2) (2-4) | | @ | Johnson C. Smith (D2) (1-5) | | | |
| MIAA | Olivet (D3) (1-4) | | @ | Kalamazoo (D3) (1-4) | | | |
| B12 | Colorado (3-2) | | @ | Kansas (4-1) | | | |
| KCAC | Ottawa (NAIA) (3-1) | | @ | Kansas Wesleyan (NAIA) (3-1) | | | |
| MAC | Ohio U. (1-5) | | @ | Kent St (1-5) | | | |
| SEC | South Carolina (4-2) | | @ | #25 Kentucky (4-1) | | | |
| SIAC | Fort Valley St (D2) (2-3) | | @ | Kentucky St (D2) (3-3) | | | |
| MidAC | Widener (D3) (2-2) | | @ | King's PA (D3) (1-3) | | | |
| PSAC | Shippensburg (D2) (3-3) | | @ | Kutztown (D2) (2-4) | | | |
| Greenville (D3) (2-3) | | @ | LaGrange (D3) (4-1) | | | |
| Apprentice (D3) (0-3) | | @ | Lake Erie (D2) (1-5) | | | |
| SIAC | Benedict (D2) (3-3) | | @ | Lane (D2) (1-5) | | | |
| MidW | Lake Forest (D3) (1-4) | | @ | Lawrence (D3) (0-4) | | | |
| Pat | Fordham (2-2) | | @ | Lehigh (1-3) | | | |
| Stony Brook (1-4) | | @ | Liberty (5-0) | | | |
| NWC | Whitworth (D3) (2-2) | | @ | Linfield (D3) (2-1) | | | |
| IIAC | Buena Vista (D3) (3-1) | | @ | Loras (D3) (3-1) | | | |
| ASWC | Mary Hardin-Baylor (D3) (4-0) | | @ | Louisiana College (D3) (2-2) | | | |
| MidAC | Albright (D3) (3-1) | | @ | Lycoming (D3) (3-1) | | | |
| St Scholastica (D3) (0-3) | | @ | Macalester (D3) (2-3) | | | |
| Westminster MO (D3) (2-2) | | @ | MacMurray (D3) (1-4) | | | |
| HCA | Defiance (D3) (0-4) | | @ | Manchester (D3) (2-2) | | | |
| Aurora (D3) (3-1) | | @ | Maranatha Baptist (D3) (0-4) | | | |
| MSFA | St Francis IN (NAIA) (5-0) | | @ | Marian (NAIA) (3-2) | | | |
| OAC | John Carroll (D3) (3-1) | | @ | Marietta (D3) (1-3) | | | |
| Bryant (D2) (3-2) | | @ | Marist (1-5) | | | |
| SAC | Newberry (D2) (3-2) | | @ | Mars Hill (D2) (3-3) | | | |
| NSIC | Minn St-Moorhead (D3) (1-5) | | @ | Mary (D2) (2-4) | | | |
| NEF | Westfield St (D3) (2-3) | | @ | Mass Maritime (D3) (0-5) | | | |
| DAC | Dickinson St (NAIA) (2-3) | | @ | Mayville St (NAIA) (1-4) | | | |
| MSFA | Trinity Int'l (NAIA) (1-4) | | @ | McKendree (NAIA) (1-3) | | | |
| ASWC | Howard Payne (D3) (1-3) | | @ | McMurry (D3) (0-5) | | | |
| SLC | Texas St-San Marcos (3-2) | | @ | McNeese St (3-1) | | | |
| KCAC | Sterling (NAIA) (2-2) | | @ | McPherson (NAIA) (2-2) | | | |
| Puget Sound (D3) (2-1) | | @ | Menlo (D3) (1-4) | | | |
| LL | WPI (D3) (4-1) | | @ | Merchant Marine (D3) (2-3) | | | |
| RMAC | Colorado St-Pueblo (D2) (2-3) | | @ | Mesa St (D2) (4-2) | | | |
| USASC | Averett (D3) (1-3) | | @ | Methodist (D3) (1-3) | | | |
| Central Florida (2-3) | | @ | Miami FL (2-3) | | | |
| Toledo (1-4) | | @ | Michigan (2-3) | | | |
| LSC | Tarleton St (D2) (5-1) | | @ | Midwestern St (D2) (4-1) | | | |
| PSAC | Cheyney (D2) (0-6) | | @ | Millersville (D2) (0-6) | | | |
| CCIW | Illinois Wesleyan (D3) (3-1) | | @ | Millikin (D3) (2-2) | | | |
| Concordia-St Paul (D2) (3-3) | | @ | Minn St-Mankato (D2) (4-2) | | | |
| St Cloud St (D2) (4-2) | | @ | Minnesota-Crookston (D2) (2-4) | | | |
| Northern St SD (D2) (1-5) | | @ | Minnesota-Duluth (D2) (6-0) | | | |
| SEC | #10 Vanderbilt (5-0) | | @ | Mississippi St (1-4) | | | |
| SWAC | Alcorn St (1-5) | | @ | Mississippi Valley St (1-2) | | | |
| B12 | #15 Oklahoma St (5-0) | | @ | #3 Missouri (5-0) | | | |
| MVC | Youngstown St (1-4) | | @ | Missouri St (0-3) | | | |
| BSky | Weber St (4-2) | | @ | Montana St (3-2) | | | |
| Front | Rocky Mountain (NAIA) (2-4) | | @ | Montana St-Northern (NAIA) (4-1) | | | |
| Eastern Oregon (NAIA) (2-3) | | @ | Montana Tech (NAIA) (1-5) | | | |
| GPAC | Hastings (NAIA) (4-2) | | @ | Morningside (NAIA) (4-0) | | | |
| OAC | Capital (D3) (4-0) | | @ | Mount Union (D3) (4-0) | | | |
| HCA | Anderson (D3) (2-2) | | @ | Mt St Joseph (D3) (3-1) | | | |
| Juniata (D3) (1-4) | | @ | Muhlenberg (D3) (4-0) | | | |
| OVC | Tennessee Tech (3-3) | | @ | Murray St (2-4) | | | |
| GPAC | Dana (NAIA) (1-4) | | @ | Nebraska Wesleyan (NAIA) (1-3) | | | |
| RMAC | New Mexico Highlands (D2) (1-5) | | @ | Nebraska-Kearney (D2) (3-3) | | | |
| Missouri Western (D2) (2-4) | | @ | Nebraska-Omaha (D2) (3-2) | | | |
| WAC | New Mexico St (2-2) | | @ | Nevada (3-2) | | | |
| CAAF | William & Mary (2-2) | | @ | New Hampshire (4-0) | | | |
| Notre Dame (4-1) | | @ | #25 North Carolina (4-1) | | | |
| MEAC | Morgan St (2-3) | | @ | North Carolina A&T (2-4) | | | |
| Western Illinois (3-2) | | @ | North Dakota St (3-1) | | | |
| CCIW | North Central (D3) (4-0) | | @ | North Park (D3) (1-3) | | | |
| SBC | Louisiana-Lafayette (2-3) | | @ | North Texas (0-5) | | | |
| CAAF | Massachusetts (3-2) | | @ | Northeastern (2-3) | | | |
| BSky | Portland St (2-3) | | @ | Northern Arizona (4-1) | | | |
| BSky | Idaho St (0-5) | | @ | Northern Colorado (0-4) | | | |
| MAC | Miami OH (1-4) | | @ | Northern Illinois (2-3) | | | |
| MVC | Illinois St (2-2) | | @ | Northern Iowa (2-2) | | | |
| B10 | #20 Michigan St (5-1) | | @ | #19 Northwestern (5-0) | | | |
| GPAC | Midland Lutheran (NAIA) (4-1) | | @ | Northwestern IA (NAIA) (4-1) | | | |
| UMWAC | Martin Luther (NAIA) (4-1) | | @ | Northwestern MN (NAIA) (4-1) | | | |
| SLC | Nicholls St (0-1) | | @ | Northwestern St (3-2) | | | |
| GLIAC | Ashland (D2) (4-2) | | @ | Northwood (D2) (1-4) | | | |
| E8 | Ithaca (D3) (3-1) | | @ | Norwich (D3) (2-3) | | | |
| MSFA | St Xavier (NAIA) (3-2) | | @ | Ohio Dominican (NAIA) (3-2) | | | |
| B10 | Purdue (2-3) | | @ | #16 Ohio State (5-1) | | | |
| NCA | Kenyon (D3) (1-4) | | @ | Ohio Wesleyan (D3) (0-4) | | | |
| P10 | UCLA (2-3) | | @ | Oregon (4-2) | | | |
| P10 | Washington St (1-5) | | @ | Oregon St (2-3) | | | |
| OAC | Baldwin-Wallace (D3) (2-2) | | @ | Otterbein (D3) (4-0) | | | |
| Gustavus Adolphus (D3) (2-2) | | @ | Pacific Lutheran (D3) (1-2) | | | |
| CSFL | NW Oklahoma St (NAIA) (3-1) | | @ | Peru St (NAIA) (2-4) | | | |
| MSC | Bethel TN (NAIA) (1-3) | | @ | Pikeville (NAIA) (1-4) | | | |
| MAIAA | Truman St (D2) (3-2) | | @ | Pittsburg St (D2) (5-1) | | | |
| SWAC | Alabama St (1-3) | | @ | Prairie View A&M (4-0) | | | |
| 1AAInd | North Carolina Central (1-4) | | @ | Presbyterian (2-4) | | | |
| MSFA | Olivet Nazarene (NAIA) (2-3) | | @ | Quincy (NAIA) (2-3) | | | |
| SCIAC | Occidental (D3) (3-0) | | @ | Redlands (D3) (3-0) | | | |
| CAAF | James Madison (5-1) | | @ | Richmond (4-2) | | | |
| MidW | Beloit (D3) (3-2) | | @ | Ripon (D3) (4-1) | | | |
| NE | Duquesne (2-2) | | @ | Robert Morris (1-4) | | | |
| Concordia IL (D3) (1-3) | | @ | Rockford (D3) (0-4) | | | |
| NJAC | Western Conn St (D3) (2-2) | | @ | Rowan (D3) (3-1) | | | |
| Tiffin (D2) (1-5) | | @ | Saginaw Valley St (D2) (3-2) | | | |
| NEF | Nichols (D3) (2-3) | | @ | Salve Regina (D3) (2-2) | | | |
| Appalachian St (3-2) | | @ | Samford (3-2) | | | |
| Pio | Morehead St (3-2) | | @ | San Diego (5-0) | | | |
| MW | Air Force (3-2) | | @ | San Diego St (1-4) | | | |
| WAC | Utah St (1-4) | | @ | San Jose St (3-2) | | | |
| Charleston Southern (2-3) | | @ | Savannah St (3-3) | | | |
| West Virginia St (D2) (5-0) | | @ | Seton Hill (NAIA) (6-0) | | | |
| WVIAC | Concord (D2) (0-6) | | @ | Shepherd (D2) (2-4) | | | |
| MSC | Lambuth (NAIA) (3-2) | | @ | Shorter (NAIA) (4-1) | | | |
| GPAC | Briar Cliff (NAIA) (1-4) | | @ | Sioux Falls (NAIA) (5-0) | | | |
| CUSA | #22 Tulsa (5-0) | | @ | SMU (1-5) | | | |
| MEAC | Norfolk St (2-3) | | @ | South Carolina St (4-2) | | | |
| Missouri S&T (D2) (3-2) | | @ | South Dakota (2-4) | | | |
| DAC | Jamestown (NAIA) (3-2) | | @ | South Dakota Tech (NAIA) (4-1) | | | |
| GSC | Arkansas Tech (D2) (3-2) | | @ | Southern Arkansas (D2) (0-5) | | | |
| P10 | Arizona St (2-3) | | @ | #8 Southern Cal (3-1) | | | |
| MVC | Indiana St (0-5) | | @ | Southern Illinois (2-2) | | | |
| #14 Boise St (4-0) | | @ | Southern Miss (2-3) | | | |
| East Central OK (D2) (1-5) | | @ | Southern Nazarene (NAIA) (2-3) | | | |
| Western Oregon (D2) (3-3) | | @ | Southern Oregon (NAIA) (1-4) | | | |
| SWAC | Texas Southern (3-3) | | @ | Southern U. (3-2) | | | |
| Frostburg St (D3) (1-3) | | @ | Southern Virginia (NAIA) (1-5) | | | |
| KCAC | Bethel KS (NAIA) (3-1) | | @ | Southwestern KS (NAIA) (0-4) | | | |
| MSFA | Iowa Wesleyan (NAIA) (2-3) | | @ | St Francis IL (NAIA) (4-1) | | | |
| NE | Sacred Heart (5-0) | | @ | St Francis PA (0-5) | | | |
| Salisbury (D3) (4-1) | | @ | St John Fisher (D3) (3-2) | | | |
| MIA | Hamline (D3) (1-3) | | @ | St John's MN (D3) (3-2) | | | |
| Haskell (NAIA) (2-4) | | @ | St Mary KS (NAIA) (2-2) | | | |
| MidW | Monmouth IL (D3) (5-0) | | @ | St Norbert (D3) (4-1) | | | |
| CIAA | Virginia St (D2) (2-4) | | @ | St Paul's (D2) (4-2) | | | |
| P10 | Arizona (4-1) | | @ | Stanford (3-3) | | | |
| Kentucky Wesleyan (D2) (2-3) | | @ | Stephen F. Austin (2-3) | | | |
| Edward Waters (NAIA) (1-3) | | @ | Stillman (D2) (1-5) | | | |
| Rochester (D3) (1-3) | | @ | Susquehanna (D3) (2-3) | | | |
| Grand View (NAIA) (1-5) | | @ | SW Baptist (D2) (3-3) | | | |
| LSC | Northeastern St OK (D2) (0-6) | | @ | SW Oklahoma St (D2) (1-5) | | | |
| LSC | TAMU-Commerce (D2) (3-3) | | @ | TAMU-Kingsville (D2) (4-2) | | | |
| MSFA | Malone (NAIA) (2-1) | | @ | Taylor (NAIA) (2-3) | | | |
| B12 | #3 Oklahoma (5-0) | | vs | #4 Texas (5-0) | | | Dallas TX |
| B12 | Kansas St (3-2) | | @ | Texas A&M (2-3) | | | |
| ASWC | Sul Ross St (D3) (2-2) | | @ | Texas Lutheran (D3) (2-3) | | | |
| B12 | Nebraska (3-2) | | @ | #12 Texas Tech (5-0) | | | |
| SoCon | Elon (5-1) | | @ | The Citadel (3-2) | | | |
| TPAC | Bethany WV (D3) (1-3) | | @ | Thiel (D3) (0-5) | | | |
| St Vincent (D3) (1-4) | | @ | Thomas More (D3) (3-1) | | | |
| CAAF | Rhode Island (2-4) | | @ | Towson (2-4) | | | |
| MIAA | Alma (D3) (2-2) | | @ | Trine (D3) (4-0) | | | |
| NESCAA | Tufts (D3) (2-1) | | @ | Trinity CT (D3) (3-0) | | | |
| SCAC | Rhodes (D3) (2-2) | | @ | Trinity TX (D3) (4-0) | | | |
| Brevard (D2) (1-4) | | @ | Tusculum (D2) (4-2) | | | |
| SIAC | Morehouse (D2) (3-2) | | @ | Tuskegee (D2) (5-0) | | | |
| GWest | Southern Utah (3-3) | | @ | UC-Davis (2-4) | | | |
| MSC | Cumberlands KY (NAIA) (4-1) | | @ | Union KY (NAIA) (5-0) | | | |
| CUSA | Tulane (2-3) | | @ | UTEP (2-3) | | | |
| Mount Ida (D3) (2-2) | | @ | Utica (D3) (1-3) | | | |
| WIAC | UW-Eau Claire (D3) (3-1) | | @ | UW-La Crosse (D3) (0-4) | | | |
| WIAC | UW-Whitewater (D3) (4-0) | | @ | UW-River Falls (D3) (2-2) | | | |
| WIAC | UW-Platteville (D3) (2-2) | | @ | UW-Stevens Point (D3) (3-1) | | | |
| WIAC | UW-Oshkosh (D3) (2-1) | | @ | UW-Stout (D3) (3-1) | | | |
| Pio | Davidson (2-2) | | @ | Valparaiso (1-3) | | | |
| East Carolina (3-2) | | @ | Virginia (2-3) | | | |
| CIAA | Lincoln PA (D2) (0-5) | | @ | Virginia Union (D2) (4-2) | | | |
| MSC | Campbellsville (NAIA) (1-4) | | @ | Virginia-Wise (NAIA) (4-1) | | | |
| BigS | Coastal Carolina (3-3) | | @ | VMI (2-3) | | | |
| NE | Monmouth NJ (3-3) | | @ | Wagner (2-3) | | | |
| Luther (D3) (2-2) | | @ | Waldorf (NAIA) (1-5) | | | |
| MSFA | Urbana (NAIA) (1-4) | | @ | Walsh (NAIA) (1-4) | | | |
| MAIAA | Emporia St (D2) (3-3) | | @ | Washburn (D2) (4-2) | | | |
| Wabash (D3) (4-0) | | @ | Washington U. (D3) (3-1) | | | |
| GLIAC | Northern Michigan (D2) (1-4) | | @ | Wayne St MI (D2) (4-2) | | | |
| NSIC | Bemidji St (D2) (2-4) | | @ | Wayne St NE (D2) (4-2) | | | |
| TPAC | Westminster PA (D3) (3-2) | | @ | Waynesburg (D3) (2-2) | | | |
| C.W. Post (D2) (1-5) | | @ | West Chester (D2) (4-2) | | | |
| WVIAC | Glenville St (D2) (3-3) | | @ | West Liberty St (D2) (4-2) | | | |
| BigE | Syracuse (1-4) | | @ | West Virginia (3-2) | | | |
| #13 Ball St (6-0) | | @ | Western Kentucky (2-4) | | | |
| NEF | UMass-Dartmouth (D3) (3-2) | | @ | Western New England (D3) (0-5) | | | |
| RMAC | Colorado Mines (D2) (4-2) | | @ | Western St CO (D2) (2-3) | | | |
| NCC | Central Washington (D2) (5-1) | | vs | Western Washington (D2) (3-1) | | | Seattle WA |
| Chapman (D3) (3-0) | | @ | Whittier (D3) (1-2) | | | |
| NWC | Lewis & Clark (D3) (1-3) | | @ | Willamette (D3) (5-0) | | | |
| HAAC | Baker (NAIA) (3-2) | | @ | William Jewell (NAIA) (2-4) | | | |
| Morrisville St (D3) (0-4) | | @ | William Paterson (D3) (1-3) | | | |
| MSFA | St Ambrose (NAIA) (3-2) | | @ | William Penn (NAIA) (3-2) | | | |
| NESCAA | Middlebury (D3) (2-1) | | @ | Williams (D3) (2-1) | | | |
| OAC | Muskingum (D3) (2-2) | | @ | Wilmington (D3) (1-3) | | | |
| SAC | Lenoir-Rhyne (D2) (3-3) | | @ | Wingate (D2) (6-0) | | | |
| Upper Iowa (D2) (1-5) | | @ | Winona St (D2) (3-3) | | | |
| B10 | #5 Penn State (6-0) | | @ | Wisconsin (3-2) | | | |
| Lakeland (D3) (1-3) | | @ | Wisconsin Lutheran (D3) (2-2) | | | |
| NCA | Earlham (D3) (0-4) | | @ | Wittenberg (D3) (3-1) | | | |
| SoCon | Chattanooga (1-5) | | @ | Wofford (3-1) | | | |
| NEF | Maine Maritime (D3) (3-2) | | @ | Worcester St (D3) (1-4) | | | |
| UNC-Pembroke (D2) (5-1) | | @ | WV Wesleyan (D2) (1-5) | | | |
| MW | #11 Utah (6-0) | | @ | Wyoming (2-4) | | | |
| Sunday, 12 Oct 2008 |
| CIAA | Fayetteville St (D2) (5-1) | | @ | Shaw (D2) (3-3) | | | |