| 9/1/2007 | Prairie View | 34 | @ | Texas Southern | 14 | SWAC | |||
| 9/8/2007 | Alabama St | 21 | @ | Texas Southern | 10 | SWAC | |||
| 9/13/2007 | Texas Southern | 7 | @ | Jackson St | 28 | SWAC | |||
| 9/22/2007 | Texas Southern | 12 | @ | UTEP | 52 | ||||
| 9/29/2007 | Texas Southern | 24 | @ | Alabama A&M | 48 | SWAC | |||
| 10/13/2007 | Alcorn St | 22 | @ | Texas Southern | 20 | SWAC | |||
| 10/20/2007 | Texas Southern | 35 | @ | MS Valley St | 37 | SWAC | |||
| 10/27/2007 | Texas Southern | 9 | @ | Grambling | 57 | SWAC | |||
| 11/3/2007 | Southern Univ | 56 | @ | Texas Southern | 7 | SWAC | |||
| 11/17/2007 | Ark Pine Bluff | 20 | @ | Texas Southern | 10 | SWAC | |||
| 11/24/2007 | Texas Southern | 6 | @ | Houston | 59 |