| 9/2/2006 | Syracuse | 10 | @ | #14 Wake Forest | 20 | ||||
| 9/9/2006 | Duke | 13 | @ | #14 Wake Forest | 14 | ACC | |||
| 9/16/2006 | #14 Wake Forest | 24 | @ | Connecticut | 13 | ||||
| 9/23/2006 | #14 Wake Forest | 27 | @ | Mississippi | 3 | ||||
| 9/30/2006 | Liberty | 14 | @ | #14 Wake Forest | 34 | ||||
| 10/7/2006 | Clemson | 27 | @ | #14 Wake Forest | 17 | ACC | |||
| 10/14/2006 | #14 Wake Forest | 25 | @ | North Carolina St | 23 | ACC | |||
| 10/28/2006 | #14 Wake Forest | 24 | @ | North Carolina | 17 | ACC | |||
| 11/4/2006 | #23 Boston College | 14 | @ | #14 Wake Forest | 21 | ACC | |||
| 11/11/2006 | #14 Wake Forest | 30 | @ | Florida St | 0 | ACC | |||
| 11/18/2006 | #14 Virginia Tech | 27 | @ | #14 Wake Forest | 6 | ACC | |||
| 11/25/2006 | #14 Wake Forest | 38 | @ | Maryland | 24 | ACC | |||
| 12/2/2006 | #14 Wake Forest | 9 | vs | #25 Georgia Tech | 6 | ACC | ACC Championship (Jacksonville FL) | ||
| 1/2/2007 | #5 Louisville | 24 | vs | #14 Wake Forest | 13 | Orange |