| 10/24/2020 | Nebraska | at | Ohio State | |||||
| 10/31/2020 | Ohio State | at | Penn State | |||||
| 11/7/2020 | Rutgers | at | Ohio State | |||||
| 11/14/2020 | Ohio State | at | Maryland | |||||
| 11/21/2020 | Indiana | at | Ohio State | |||||
| 11/28/2020 | Ohio State | at | Illinois | |||||
| 12/5/2020 | Ohio State | at | Michigan State | |||||
| 12/12/2020 | Michigan | at | Ohio State |