| 10/8/2020 | Tulane (2-2,0-2) | 31 | at | Houston | 49 | |||
| 10/16/2020 | BYU (4-0) | at | Houston | Ind | ||||
| 10/24/2020 | Houston | at | Navy (2-2,2-0) | |||||
| 10/31/2020 | UCF (2-1,1-1) | at | Houston | |||||
| 11/7/2020 | Houston | at | Cincinnati (3-0,1-0) | |||||
| 11/14/2020 | South Florida (1-3,0-2) | at | Houston | |||||
| 11/21/2020 | Houston | at | SMU (4-0,1-0) | |||||
| 11/28/2020 | Tulsa (1-1,1-0) | at | Houston | |||||
| 12/5/2020 | Houston | at | Memphis (1-1,0-1) |
| vs Houston | vs Other Opponents | Houston compared to OOs | |
| Record: | 0-1 | 20-9 | |
| Points Scored: | 31.00 | 32.14 | 1.14 |
| Points Allowed: | 49.00 | 24.34 | 24.66 |
| Margin: | -18.00 | 7.80 | 25.80 |
| Total Points: | 80.00 | 56.48 | 23.52 |