| 8/24/2024 | SE Missouri State | 37 | vs | North Alabama (3-9) | 15 | Montgomery AL | vs UAC | |
| 8/31/2024 | SE Missouri State | 16 | at | New Mexico State (3-9) | 23 | at CUSA | ||
| 9/7/2024 | Tennessee-Martin (9-5,6-2) | 42 | at | SE Missouri State | 45 | |||
| 9/21/2024 | SE Missouri State | 38 | at | Southern Illinois (4-8) | 21 | at MVC | ||
| 9/28/2024 | Northwestern State (0-12) | 0 | at | SE Missouri State | 19 | SLC | ||
| 10/5/2024 | SE Missouri State | 38 | at | Eastern Illinois (3-9,2-6) | 27 | |||
| 10/12/2024 | Tennessee Tech (7-5,6-2) | 3 | at | SE Missouri State | 34 | |||
| 10/19/2024 | SE Missouri State | 26 | at | Charleston Southern (1-11,0-8) | 13 | |||
| 10/26/2024 | Gardner-Webb (4-8,3-5) | 24 | at | SE Missouri State | 30 | |||
| 11/9/2024 | SE Missouri State | 12 | at | Lindenwood (5-7,4-4) | 24 | |||
| 11/16/2024 | Western Illinois (4-8,3-5) | 45 | at | SE Missouri State | 54 | |||
| 11/23/2024 | SE Missouri State | 21 | at | Tennessee State (9-4,6-2) | 28 | |||
| 11/30/2024 | Illinois State (10-4) | 35 | at | SE Missouri State | 27 | FCS Championship Round 1 | MVC |
| vs SE Missouri State | vs Other Opponents | SE Missouri State compared to OOs | |
| Record: | 4-9 | 58-90 | |
| Points Scored: | 23.08 | 23.50 | 0.42 |
| Points Allowed: | 30.54 | 30.36 | 0.18 |
| Margin: | -7.46 | -6.86 | 0.60 |
| Total Points: | 53.62 | 53.86 | -0.24 |