| 8/29/2024 | Nebraska-Kearney | 18 | at | Chadron State | 6 | @ RMAC | ||
| Washburn | 14 | at | Emporia State | 30 | ||||
| Missouri Southern | 11 | at | Midwestern State | 18 | @ LSC | |||
| Missouri Western | 33 | at | Northeastern State | 31 | @ D2Ind | |||
| Minnesota State-Mankato | 36 | at | Northwest Missouri State | 22 | NSIC | |||
| 8/30/2024 | Angelo State | 7 | at | Fort Hays State | 21 | LSC | ||
| 8/31/2024 | Ferris State | 3 | at | Pittsburg State | 19 | GLIAC | ||
| 9/7/2024 | Northeastern State | 21 | at | Central Missouri | 63 | D2Ind | ||
| Langston | 0 | at | Central Oklahoma | 72 | Soon (NAIA) | |||
| Angelo State | 12 | at | Emporia State | 17 | LSC | |||
| Missouri Western | 16 | at | Fort Hays State | 30 | ||||
| Pittsburg State | 42 | at | Missouri Southern | 17 | ||||
| Northwest Missouri State | 14 | at | Nebraska-Kearney | 21 | ||||
| 9/14/2024 | Central Missouri | 40 | at | Central Oklahoma | 57 | |||
| Missouri Southern | 27 | at | Missouri Western | 35 | ||||
| Fort Hays State | 20 | at | Northwest Missouri State | 32 | ||||
| Emporia State | 24 | at | Pittsburg State | 21 | ||||
| Colorado Mines | 31 | at | Washburn | 28 | RMAC | |||
| 9/21/2024 | Central Missouri | 32 | at | Davenport | 31 | @ GLIAC | ||
| Missouri Western | 27 | at | Emporia State | 30 | ||||
| Northeastern State | 0 | at | Fort Hays State | 37 | D2Ind | |||
| Northwest Missouri State | 59 | at | Missouri Southern | 0 | ||||
| Central Oklahoma | 32 | at | Nebraska-Kearney | 17 | ||||
| Pittsburg State | 39 | at | Washburn | 31 | ||||
| 9/28/2024 | Nebraska-Kearney | 35 | at | Central Missouri | 36 | |||
| Fort Hays State | 24 | at | Central Oklahoma | 49 | ||||
| Washburn | 24 | at | Missouri Western | 16 | ||||
| Missouri Southern | 27 | vs | Northeastern State | 20 | Broken Arrow OK | vs D2Ind | ||
| Emporia State | 9 | at | Northwest Missouri State | 14 | ||||
| 10/5/2024 | Northeastern State | 14 | at | Emporia State | 48 | D2Ind | ||
| Central Missouri | 21 | at | Fort Hays State | 31 | ||||
| Central Oklahoma | 59 | at | Missouri Southern | 24 | ||||
| Missouri Western | 20 | at | Pittsburg State | 31 | ||||
| Nebraska-Kearney | 35 | at | Southwest Minnesota State | 0 | @ NSIC | |||
| Northwest Missouri State | 51 | at | Washburn | 34 | ||||
| 10/12/2024 | Missouri Western | 38 | at | Central Missouri | 28 | |||
| Northwest Missouri State | 20 | at | Central Oklahoma | 48 | ||||
| Washburn | 7 | at | Fort Hays State | 38 | ||||
| Emporia State | 49 | at | Missouri Southern | 30 | ||||
| Pittsburg State | 20 | at | Nebraska-Kearney | 10 | ||||
| 10/19/2024 | Nebraska-Kearney | 24 | at | Missouri Western | 23 | |||
| Central Oklahoma | 64 | at | Northeastern State | 57 | @ D2Ind | |||
| Central Missouri | 35 | at | Northwest Missouri State | 30 | ||||
| Fort Hays State | 17 | at | Pittsburg State | 18 | ||||
| Missouri Southern | 21 | at | Washburn | 42 | ||||
| 10/26/2024 | Washburn | 28 | at | Central Missouri | 31 | |||
| Pittsburg State | 35 | at | Central Oklahoma | 21 | ||||
| Missouri Southern | 9 | at | Fort Hays State | 53 | ||||
| Emporia State | 42 | at | Nebraska-Kearney | 35 | ||||
| 11/2/2024 | Fort Hays State | 36 | at | Emporia State | 7 | |||
| Central Oklahoma | 37 | at | Missouri Western | 34 | OT | |||
| Northeastern State | 26 | at | Northwest Missouri State | 44 | D2Ind | |||
| Central Missouri | 37 | at | Pittsburg State | 13 | ||||
| Nebraska-Kearney | 14 | at | Washburn | 13 | ||||
| 11/9/2024 | Central Missouri | 45 | at | Emporia State | 36 | |||
| Nebraska-Kearney | 13 | at | Missouri Southern | 24 | ||||
| Northwest Missouri State | 33 | at | Missouri Western | 23 | ||||
| Central Oklahoma | 28 | at | Washburn | 27 | ||||
| 11/16/2024 | Missouri Southern | 47 | at | Central Missouri | 62 | |||
| Emporia State | 38 | at | Central Oklahoma | 55 | ||||
| Quincy | 16 | at | Missouri Western | 31 | GLV | |||
| Fort Hays State | 27 | at | Nebraska-Kearney | 20 | ||||
| Washburn | 35 | at | Northeastern State | 28 | @ D2Ind | |||
| Pittsburg State | 23 | at | Northwest Missouri State | 7 | ||||
| 11/23/2024 | Ouachita | 31 | at | Central Oklahoma | 38 | OT | GAC | |
| Harding | 48 | at | Pittsburg State | 3 | GAC | |||
| 11/30/2024 | Central Oklahoma | 17 | at | Ferris State | 78 | D2 Playoffs Round 2 | @ GLIAC | |
| 12/7/2024 | Central Missouri | 39 | vs | Texas-Permian Basin | 37 | 2OT | Heritage Bowl | vs LSC |