| 8/26/2023 | San Jose State (7-6) | 28 | at | Southern California | 56 | MW | ||
| 9/2/2023 | Nevada (2-10) | 14 | at | Southern California | 66 | MW | ||
| 9/9/2023 | Stanford (3-9,2-7) | 10 | at | Southern California | 56 | |||
| 9/23/2023 | Southern California | 42 | at | Arizona State (3-9,2-7) | 28 | |||
| 9/30/2023 | Southern California | 48 | at | Colorado (4-8,1-8) | 41 | |||
| 10/7/2023 | Arizona (10-3,7-2) | 41 | at | Southern California | 43 | 3OT | ||
| 10/14/2023 | Southern California | 20 | at | Notre Dame (10-3) | 48 | at ND | ||
| 10/21/2023 | Utah (8-5,5-4) | 34 | at | Southern California | 32 | |||
| 10/28/2023 | Southern California | 50 | at | California (6-7,4-5) | 49 | |||
| 11/4/2023 | Washington (14-1,10-0) | 52 | at | Southern California | 42 | |||
| 11/11/2023 | Southern California | 27 | at | Oregon (12-2,8-2) | 36 | |||
| 11/18/2023 | UCLA (8-5,4-5) | 38 | at | Southern California | 20 | |||
| 12/27/2023 | Louisville (10-4) | 28 | vs | Southern California | 42 | Holiday Bowl - San Diego CA | ACC |
| vs Southern California | vs Other Opponents | Southern California compared to OOs | |
| Record: | 5-8 | 92-64 | |
| Points Scored: | 34.38 | 29.22 | -5.16 |
| Points Allowed: | 41.85 | 23.97 | 17.88 |
| Margin: | -7.47 | 5.25 | 12.72 |
| Total Points: | 76.23 | 53.19 | 23.04 |