| 9/2/2023 | South Florida | 24 | at | Western Kentucky (8-5) | 41 | at CUSA | ||
| 9/9/2023 | Florida A&M (12-1) | 24 | at | South Florida | 38 | SWAC (1AA) | ||
| 9/16/2023 | Alabama (12-2) | 17 | at | South Florida | 3 | SEC | ||
| 9/23/2023 | Rice (6-7,4-4) | 29 | at | South Florida | 42 | |||
| 9/30/2023 | South Florida | 44 | at | Navy (5-7,4-4) | 30 | |||
| 10/7/2023 | South Florida | 35 | at | UAB (4-8,3-5) | 56 | |||
| 10/14/2023 | Florida Atlantic (4-8,3-5) | 56 | at | South Florida | 14 | |||
| 10/21/2023 | South Florida | 24 | at | Connecticut (3-9) | 21 | at Ind | ||
| 11/4/2023 | South Florida | 50 | at | Memphis (10-3,6-2) | 59 | |||
| 11/11/2023 | Temple (3-9,1-7) | 23 | at | South Florida | 27 | |||
| 11/17/2023 | South Florida | 21 | at | Texas-San Antonio (9-4,7-1) | 49 | |||
| 11/25/2023 | UNC-Charlotte (3-9,2-6) | 14 | at | South Florida | 48 | |||
| 12/21/2023 | South Florida | 45 | vs | Syracuse (6-7) | 0 | Boca Raton Bowl | vs ACC |
| vs South Florida | vs Other Opponents | South Florida compared to OOs | |
| Record: | 6-7 | 79-72 | |
| Points Scored: | 32.23 | 26.60 | -5.63 |
| Points Allowed: | 31.92 | 26.16 | 5.76 |
| Margin: | 0.31 | 0.44 | 0.13 |
| Total Points: | 64.15 | 52.76 | 11.39 |