| 9/1/2018 | Eureka (9-2) | 49 | at | Knox | 24 | NAC | ||
| 9/8/2018 | Knox | 20 | at | Beloit (1-9,1-8) | 23 | |||
| 9/22/2018 | Knox | 3 | at | Ripon (7-3,6-2) | 28 | |||
| 9/29/2018 | St Norbert (10-2,8-0) | 34 | at | Knox | 0 | |||
| 10/6/2018 | Lake Forest (6-4,5-3) | 35 | at | Knox | 0 | |||
| 10/13/2018 | Knox | 28 | at | Grinnell (2-8,1-8) | 7 | |||
| 10/20/2018 | Illinois College (4-6,4-4) | 6 | at | Knox | 20 | |||
| 10/27/2018 | Knox | 7 | at | Cornell IA (5-5,4-4) | 22 | |||
| 11/3/2018 | Monmouth IL (8-2,7-1) | 40 | at | Knox | 7 | |||
| 11/10/2018 | Knox | 19 | at | Ripon (7-3,6-2) | 38 |
| vs Knox | vs Other Opponents | Knox compared to OOs | |
| Record: | 8-2 | 49-42 | |
| Points Scored: | 28.20 | 29.80 | 1.60 |
| Points Allowed: | 12.80 | 26.91 | -14.11 |
| Margin: | 15.40 | 2.89 | -12.51 |
| Total Points: | 41.00 | 56.71 | -15.71 |