| 9/1/2018 | Adrian | 17 | at | Ohio Northern (5-5) | 34 | at OAC | ||
| 9/8/2018 | Buffalo State (1-9) | 27 | at | Adrian | 56 | E8 | ||
| 9/15/2018 | Adrian | 27 | at | Aurora (5-5) | 5 | at NAC | ||
| 9/29/2018 | Adrian | 30 | at | Kalamazoo (7-3,4-3) | 31 | |||
| 10/6/2018 | Olivet (6-4,4-3) | 50 | at | Adrian | 22 | |||
| 10/13/2018 | Adrian | 28 | at | Alma (2-8,1-6) | 23 | |||
| 10/20/2018 | Albion (7-3,4-3) | 49 | at | Adrian | 42 | |||
| 10/27/2018 | Finlandia (0-10,0-7) | 6 | at | Adrian | 49 | |||
| 11/3/2018 | Adrian | 27 | at | Trine (10-1,7-0) | 42 | |||
| 11/10/2018 | Hope (8-2,6-1) | 33 | at | Adrian | 14 |
| vs Adrian | vs Other Opponents | Adrian compared to OOs | |
| Record: | 6-4 | 45-46 | |
| Points Scored: | 30.00 | 29.79 | -0.21 |
| Points Allowed: | 31.20 | 29.18 | 2.02 |
| Margin: | -1.20 | 0.61 | 1.81 |
| Total Points: | 61.20 | 58.97 | 2.23 |