| 9/1/2018 | Charleston Southern | 6 | at | Florida (10-3) | 53 | at SEC | ||
| 9/22/2018 | Elon (6-5) | 31 | at | Charleston Southern | 22 | CAAF | ||
| 9/29/2018 | Charleston Southern | 48 | at | Hampton (7-3) | 14 | at Ind1AA | ||
| 10/6/2018 | Charleston Southern | 3 | at | Savannah State (2-8) | 23 | at MEAC | ||
| 10/13/2018 | Virginia U-Lynchburg (3-7) | 6 | at | Charleston Southern | 58 | None (Unk?) | ||
| 10/20/2018 | Presbyterian (2-8,0-5) | 7 | at | Charleston Southern | 41 | |||
| 10/27/2018 | Kennesaw St (11-2,5-0) | 38 | at | Charleston Southern | 10 | |||
| 11/3/2018 | Charleston Southern | 3 | at | Monmouth NJ (8-3,4-1) | 37 | |||
| 11/10/2018 | Gardner-Webb (3-8,2-3) | 0 | at | Charleston Southern | 16 | |||
| 11/17/2018 | Charleston Southern | 12 | at | Campbell (6-5,1-4) | 7 | |||
| 11/29/2018 | Charleston Southern | 14 | at | The Citadel (5-6) | 43 | at SoCon |
| vs Charleston Southern | vs Other Opponents | Charleston Southern compared to OOs | |
| Record: | 6-5 | 57-53 | |
| Points Scored: | 23.55 | 27.53 | 3.98 |
| Points Allowed: | 21.18 | 28.05 | -6.87 |
| Margin: | 2.37 | -0.52 | -2.89 |
| Total Points: | 44.73 | 55.58 | -10.85 |