| 9/1/2018 | Cal Poly | 3 | at | North Dakota State (15-0) | 49 | at MVC | ||
| 9/8/2018 | Weber State (10-3,7-1) | 24 | at | Cal Poly | 17 | |||
| 9/14/2018 | Brown (1-9) | 15 | at | Cal Poly | 44 | Ivy | ||
| 9/22/2018 | Cal Poly | 17 | at | Eastern Washington (12-3,9-1) | 70 | |||
| 9/29/2018 | Montana (6-5,4-3) | 48 | at | Cal Poly | 28 | |||
| 10/6/2018 | Cal Poly | 41 | at | Sacramento State (2-8,1-6) | 27 | |||
| 10/20/2018 | UC Davis (10-3,7-2) | 52 | at | Cal Poly | 10 | |||
| 10/27/2018 | Cal Poly | 38 | at | Northern Arizona (4-6,2-5) | 28 | |||
| 11/3/2018 | Cal Poly | 42 | at | Montana State (8-5,5-3) | 49 | |||
| 11/10/2018 | Idaho State (6-5,4-3) | 14 | at | Cal Poly | 37 | |||
| 11/17/2018 | Southern Utah (1-10,1-7) | 24 | at | Cal Poly | 38 |
| vs Cal Poly | vs Other Opponents | Cal Poly compared to OOs | |
| Record: | 6-5 | 69-52 | |
| Points Scored: | 36.36 | 31.41 | -4.95 |
| Points Allowed: | 28.64 | 27.98 | 0.66 |
| Margin: | 7.72 | 3.43 | -4.29 |
| Total Points: | 65.00 | 59.39 | 5.61 |