| 9/1/2018 | Pacific | 6 | at | Chapman | 36 | @ SCIAC | ||
| Puget Sound | 45 | at | Claremont-Mudd-Scripps | 35 | @ SCIAC | |||
| George Fox | 12 | at | Redlands | 20 | @ SCIAC | |||
| Willamette | 7 | at | Simon Fraser | 54 | @ GNWAC (D2) | |||
| La Verne | 2 | at | Whitworth | 38 | SCIAC | |||
| 9/8/2018 | Pacific Lutheran | 8 | at | Cal Lutheran | 24 | @ SCIAC | ||
| Linfield | 14 | at | Carroll MT | 21 | @ Front (NAIA) | |||
| Howard Payne | 3 | at | George Fox | 35 | ASWC | |||
| Pomona-Pitzer | 34 | at | Lewis & Clark | 21 | SCIAC | |||
| Dubuque | 21 | at | Pacific | 10 | IIAC | |||
| Redlands | 28 | at | Puget Sound | 21 | SCIAC | |||
| 9/15/2018 | Puget Sound | 56 | at | La Verne | 28 | @ SCIAC | ||
| Redlands | 0 | at | Linfield | 13 | SCIAC | |||
| Willamette | 25 | at | Occidental | 6 | @ SCIAC | |||
| Claremont-Mudd-Scripps | 7 | at | Pacific Lutheran | 10 | SCIAC | |||
| Cal Lutheran | 16 | at | Pacific | 21 | SCIAC | |||
| George Fox | 40 | at | Pomona-Pitzer | 6 | @ SCIAC | |||
| Lewis & Clark | 46 | at | Whittier | 27 | @ SCIAC | |||
| Chapman | 28 | at | Whitworth | 31 | SCIAC | |||
| 9/29/2018 | George Fox | 13 | at | Pacific | 19 | OT | ||
| Pacific Lutheran | 21 | at | Puget Sound | 28 | OT | |||
| Linfield | 14 | at | Whitworth | 19 | ||||
| Lewis & Clark | 39 | at | Willamette | 21 | ||||
| 10/6/2018 | Whitworth | 38 | at | George Fox | 14 | |||
| Puget Sound | 34 | at | Lewis & Clark | 22 | ||||
| Willamette | 0 | at | Linfield | 59 | ||||
| Pacific | 23 | at | Pacific Lutheran | 30 | ||||
| 10/13/2018 | Lewis & Clark | 26 | at | Linfield | 43 | |||
| Pacific | 23 | at | Puget Sound | 22 | ||||
| Pacific Lutheran | 13 | at | Whitworth | 55 | ||||
| George Fox | 28 | at | Willamette | 6 | ||||
| 10/20/2018 | Linfield | 14 | at | George Fox | 0 | |||
| Willamette | 20 | at | Pacific Lutheran | 33 | ||||
| Lewis & Clark | 22 | at | Pacific | 54 | ||||
| Whitworth | 47 | at | Puget Sound | 13 | ||||
| 10/27/2018 | George Fox | 17 | at | Lewis & Clark | 0 | |||
| Pacific Lutheran | 7 | at | Linfield | 41 | ||||
| Pacific | 19 | at | Whitworth | 37 | ||||
| Puget Sound | 42 | at | Willamette | 28 | ||||
| 11/3/2018 | George Fox | 35 | at | Pacific Lutheran | 7 | |||
| Willamette | 13 | at | Pacific | 44 | ||||
| Linfield | 47 | at | Puget Sound | 41 | ||||
| Lewis & Clark | 28 | at | Whitworth | 38 | ||||
| 11/10/2018 | Puget Sound | 48 | at | George Fox | 62 | |||
| Pacific Lutheran | 28 | at | Lewis & Clark | 14 | ||||
| Pacific | 7 | at | Linfield | 50 | ||||
| Whitworth | 52 | at | Willamette | 0 | ||||
| 11/17/2018 | Claremont-Mudd-Scripps | 6 | at | Whitworth | 48 | D3 Playooff Round 1 | SCIAC | |
| 11/24/2018 | Whitworth | 24 | at | St John's MN | 45 | @ MIA |