| 9/1/2018 | Taylor | 43 | at | Indiana Wesleyan | 31 | MSFA | ||
| 9/8/2018 | Livingstone | 19 | at | Allen | 0 | CIAA (D2) | ||
| Indiana Wesleyan | 61 | at | Anderson | 6 | @ HCA (D3) | |||
| Lawrence Tech | 30 | at | Wisconsin Lutheran | 22 | @ NAC (D3) | |||
| 9/15/2018 | Allen | vs | Brevard | CCD | vs USASC (D3) | |||
| Trinity Bible | 6 | at | Indiana Wesleyan | 80 | None (Unk?) | |||
| 9/22/2018 | Lindenwood-Belleville | 7 | at | Indiana Wesleyan | 44 | MSFA | ||
| 9/29/2018 | Allen | 6 | at | Clark Atlanta | 31 | @ SIAC (D2) | ||
| 10/6/2018 | Allen | 0 | at | Bluefield | 45 | @ MSC | ||
| St Francis IL | 34 | at | Indiana Wesleyan | 35 | MSFA | |||
| Lawrence Tech | 68 | at | Trinity Bible | 7 | @ None (Unk?) | |||
| 10/13/2018 | Allen | 3 | at | Lane | 13 | @ SIAC (D2) | ||
| Indiana Wesleyan | 38 | at | Lawrence Tech | 24 | ||||
| 10/20/2018 | Lawrence Tech | 7 | at | Northern Michigan | 65 | @ GLIAC (D2) | ||
| Indiana Wesleyan | 10 | at | Siena Heights | 31 | @ MSFA | |||
| 10/27/2018 | Trinity Bible | at | Lawrence Tech | CCD | None (Unk?) | |||
| Indiana Wesleyan | 40 | at | Olivet Nazarene | 36 | @ MSFA | |||
| 11/3/2018 | Indiana Wesleyan | 7 | at | Concordia MI | 55 | @ MSFA | ||
| 11/10/2018 | Virginia U-Lynchburg | 47 | at | Allen | 21 | None (Unk?) | ||
| 11/17/2018 | Allen | 10 | at | Brevard | 46 | @ USASC (D3) | ||
| Lawrence Tech | 19 | at | Indiana Wesleyan | 51 |