| 8/30/2018 | Millsaps | 18 | at | Belhaven | 3 | SAA | ||
| Wisconsin-Platteville | 59 | at | East Texas Baptist | 44 | WIAC | |||
| Trinity TX | 44 | at | McMurry | 0 | SAA | |||
| 9/1/2018 | Sul Ross State | 20 | at | Arizona Christian | 42 | @ Soon (NAIA) | ||
| Denison | 21 | at | Southwestern Texas | 42 | NCA | |||
| 9/8/2018 | Mary Hardin-Baylor | 91 | at | Albright | 7 | @ MidAC | ||
| Louisiana College | 0 | at | Alcorn State | 78 | @ SWAC (1AA) | |||
| Howard Payne | 3 | at | George Fox | 35 | @ NWC | |||
| Southwestern Texas | 37 | at | McMurry | 6 | ||||
| Hendrix | 14 | at | Texas Lutheran | 19 | SAA | |||
| Hardin-Simmons | 42 | at | Trinity TX | 33 | @ SAA | |||
| 9/15/2018 | Texas Lutheran | 23 | at | Belhaven | 0 | |||
| Southwestern Texas | 21 | at | East Texas Baptist | 51 | ||||
| McMurry | 31 | at | Howard Payne | 37 | 2OT | |||
| Hardin-Simmons | 57 | at | Louisiana College | 21 | ||||
| Mary Hardin-Baylor | 68 | at | Sul Ross State | 7 | ||||
| 9/22/2018 | East Texas Baptist | 46 | at | Belhaven | 20 | |||
| Howard Payne | 14 | at | Hardin-Simmons | 65 | ||||
| Sul Ross State | 24 | at | McMurry | 35 | ||||
| Louisiana College | 21 | at | Southwestern Texas | 19 | ||||
| Mary Hardin-Baylor | 47 | at | Texas Lutheran | 14 | ||||
| 9/29/2018 | East Texas Baptist | 17 | at | Hardin-Simmons | 59 | |||
| Belhaven | 20 | at | Howard Payne | 19 | ||||
| Southwestern Texas | 7 | at | Mary Hardin-Baylor | 77 | ||||
| Louisiana College | 49 | at | Sul Ross State | 16 | ||||
| McMurry | 7 | at | Texas Lutheran | 65 | ||||
| 10/6/2018 | McMurry | 27 | at | Belhaven | 20 | |||
| Howard Payne | 28 | at | East Texas Baptist | 54 | ||||
| Texas Lutheran | 41 | at | Louisiana College | 36 | ||||
| Hardin-Simmons | 0 | at | Mary Hardin-Baylor | 26 | ||||
| Southwestern Texas | 55 | at | Sul Ross State | 7 | ||||
| 10/12/2018 | Mary Hardin-Baylor | 55 | at | Howard Payne | 0 | |||
| 10/13/2018 | Sul Ross State | 27 | at | Hardin-Simmons | 48 | |||
| Louisiana College | 35 | at | McMurry | 23 | ||||
| Belhaven | 10 | at | Southwestern Texas | 21 | ||||
| East Texas Baptist | 21 | at | Texas Lutheran | 28 | ||||
| 10/20/2018 | Mary Hardin-Baylor | 49 | at | Belhaven | 0 | |||
| Texas Lutheran | 14 | at | Hardin-Simmons | 58 | ||||
| East Texas Baptist | 48 | at | Louisiana College | 27 | ||||
| Howard Payne | 27 | at | Sul Ross State | 28 | ||||
| 10/27/2018 | Sul Ross State | 14 | at | East Texas Baptist | 60 | |||
| Belhaven | 7 | at | Louisiana College | 42 | ||||
| McMurry | 7 | at | Mary Hardin-Baylor | 80 | ||||
| Hardin-Simmons | 49 | at | Southwestern Texas | 35 | ||||
| Howard Payne | 7 | at | Texas Lutheran | 53 | ||||
| 11/3/2018 | Hardin-Simmons | 61 | at | Belhaven | 13 | |||
| Southwestern Texas | 54 | at | Howard Payne | 17 | ||||
| Louisiana College | 7 | at | Mary Hardin-Baylor | 80 | ||||
| East Texas Baptist | 62 | at | McMurry | 7 | ||||
| Sul Ross State | 20 | at | Texas Lutheran | 63 | ||||
| 11/10/2018 | Mary Hardin-Baylor | 50 | at | East Texas Baptist | 15 | |||
| McMurry | 6 | at | Hardin-Simmons | 83 | ||||
| Howard Payne | 13 | at | Louisiana College | 45 | ||||
| Texas Lutheran | 35 | at | Southwestern Texas | 59 | ||||
| Belhaven | 8 | at | Sul Ross State | 0 | ||||
| 11/17/2018 | Hardin-Simmons | 6 | at | Mary Hardin-Baylor | 27 | D3 Playooff Round 1 | ||
| 11/24/2018 | Berry | 9 | at | Mary Hardin-Baylor | 75 | SAA | ||
| 12/1/2018 | St John's MN | 18 | at | Mary Hardin-Baylor | 21 | D3 Playoff | MIA | |
| 12/8/2018 | Wisconsin-Whitewater | 14 | at | Mary Hardin-Baylor | 31 | D3 Playoff Semifinal | WIAC | |
| 12/14/2018 | Mount Union | 16 | vs | Mary Hardin-Baylor | 24 | D3 Championship - Shenandoah TX | vs OAC |