| 9/9/2017 | DePauw | 41 | at | Mt St Joseph (6-4) | 30 | at HCA | ||
| 9/16/2017 | DePauw | 55 | at | Hiram (2-8,1-8) | 28 | |||
| 9/23/2017 | Wooster (6-4,5-4) | 24 | at | DePauw | 51 | |||
| 9/30/2017 | DePauw | 31 | at | Ohio Wesleyan (5-5,5-4) | 30 | |||
| 10/7/2017 | Oberlin (4-6,3-6) | 10 | at | DePauw | 26 | |||
| 10/14/2017 | DePauw | 26 | at | Denison (7-3,6-3) | 17 | |||
| 10/21/2017 | Wittenberg (10-1,9-0) | 52 | at | DePauw | 6 | |||
| 10/28/2017 | Allegheny (3-7,2-7) | 26 | at | DePauw | 42 | |||
| 11/4/2017 | DePauw | 37 | at | Kenyon (0-10,0-9) | 32 | |||
| 11/11/2017 | Wabash (8-2,7-2) | 22 | at | DePauw | 21 |
| vs DePauw | vs Other Opponents | DePauw compared to OOs | |
| Record: | 2-8 | 49-42 | |
| Points Scored: | 27.10 | 32.53 | 5.43 |
| Points Allowed: | 33.60 | 30.33 | 3.27 |
| Margin: | -6.50 | 2.20 | 8.70 |
| Total Points: | 60.70 | 62.86 | -2.16 |