| 9/2/2017 | Carnegie Mellon | 28 | at | Washington U (3-6) | 7 | at D3Ind | ||
| 9/9/2017 | Rochester (2-7) | 14 | at | Carnegie Mellon | 42 | LL | ||
| 9/16/2017 | Carnegie Mellon | 30 | at | Waynesburg (2-8,2-7) | 20 | |||
| 9/23/2017 | Thomas More (6-4,5-3) | 17 | at | Carnegie Mellon | 37 | |||
| 9/30/2017 | Carnegie Mellon | 45 | at | Bethany WV (2-8,2-7) | 14 | |||
| 10/7/2017 | Washington & Jefferson (11-1,9-0) | 27 | at | Carnegie Mellon | 20 | |||
| 10/14/2017 | Geneva (3-7,3-6) | 27 | at | Carnegie Mellon | 42 | |||
| 10/21/2017 | Carnegie Mellon | 42 | at | Thiel (1-9,1-8) | 10 | |||
| 10/28/2017 | Carnegie Mellon | 7 | at | Westminster PA (7-3,7-2) | 21 | |||
| 11/11/2017 | Case Western Reserve (11-1,8-0) | 41 | at | Carnegie Mellon | 34 | OT | ||
| 11/18/2017 | Muhlenberg (8-3) | 32 | vs | Carnegie Mellon | 6 | Asa Bushnell Bowl (Newark DE) | Cen |
| vs Carnegie Mellon | vs Other Opponents | Carnegie Mellon compared to OOs | |
| Record: | 4-7 | 52-50 | |
| Points Scored: | 20.91 | 27.22 | 6.31 |
| Points Allowed: | 30.27 | 25.61 | 4.66 |
| Margin: | -9.36 | 1.61 | 10.97 |
| Total Points: | 51.18 | 52.83 | -1.65 |