| 8/24/2017 | Dakota Wesleyan | 39 | at | Dakota State | 56 | GPAC | ||
| Rocky Mountain | 28 | at | Dickinson State | 43 | Front | |||
| 8/26/2017 | Hastings | 31 | at | Jamestown | 3 | GPAC | ||
| Briar Cliff | 26 | at | Waldorf | 62 | GPAC | |||
| 8/31/2017 | Mayville State | 27 | at | Buena Vista | 31 | @ IIAC (D3) | ||
| 9/2/2017 | St Francis IN | 55 | at | Jamestown | 7 | MSFA | ||
| Presentation | 40 | at | Lawrence | 10 | @ MidW (D3) | |||
| Dakota State | 24 | at | Saint Ambrose | 27 | @ MSFA | |||
| Dickinson State | 30 | at | Valley City State | 21 | ||||
| Trinity Bible | at | Waldorf | Cancelled | None (Unk?) | ||||
| 9/9/2017 | Dakota State | 49 | at | Briar Cliff | 33 | @ GPAC | ||
| Jamestown | 12 | at | Dakota Wesleyan | 49 | @ GPAC | |||
| Waldorf | 14 | at | Dordt | 59 | @ GPAC | |||
| Valley City State | 9 | at | Hastings | 47 | @ GPAC | |||
| Sterling | 44 | at | Mayville State | 40 | KCAC | |||
| Dickinson State | 3 | at | Northwestern IA | 37 | @ GPAC | |||
| Presentation | 14 | at | St John's MN | 49 | @ MIA (D3) | |||
| 9/16/2017 | Mayville State | 16 | at | Dakota State | 48 | |||
| Waldorf | 54 | at | Presentation | 47 | ||||
| Jamestown | 13 | at | Valley City State | 43 | ||||
| 9/23/2017 | Waldorf | 19 | at | Jamestown | 26 | |||
| Dickinson State | 52 | at | Mayville State | 7 | ||||
| Finlandia | at | Valley City State | Forfeit? | D3Ind (D3) | ||||
| 9/25/2017 | Presentation | 22 | vs | Dakota State | 21 | Sioux Falls SD | ||
| 9/30/2017 | Presentation | 17 | at | Dickinson State | 40 | |||
| Dakota State | 20 | at | Jamestown | 14 | OT | |||
| Montana State-Northern | 43 | vs | Mayville State | 29 | vs Front | |||
| Valley City State | 35 | at | Waldorf | 39 | ||||
| 10/7/2017 | Waldorf | 20 | at | Dakota State | 59 | |||
| Valley City State | 20 | at | Dickinson State | 35 | ||||
| Presentation | 44 | at | Mayville State | 14 | ||||
| 10/14/2017 | Waldorf | 0 | at | Dickinson State | 45 | |||
| Jamestown | 22 | at | Presentation | 40 | ||||
| Mayville State | 0 | at | Valley City State | 58 | ||||
| 10/21/2017 | Dickinson State | 44 | at | Jamestown | 13 | |||
| Dakota State | 31 | at | Valley City State | 28 | ||||
| Mayville State | 14 | at | Waldorf | 48 | ||||
| 10/28/2017 | Dickinson State | 28 | at | Dakota State | 25 | |||
| Jamestown | 27 | at | Mayville State | 14 | ||||
| Valley City State | 66 | at | Presentation | 27 | ||||
| 11/4/2017 | Valley City State | 40 | at | Jamestown | 14 | |||
| Dakota State | 34 | at | Mayville State | 6 | ||||
| Presentation | 33 | at | Waldorf | 41 | ||||
| 11/11/2017 | Mayville State | 7 | at | Dickinson State | 70 | |||
| Dakota State | 59 | at | Presentation | 21 | ||||
| Jamestown | 54 | at | Waldorf | 55 | OT | |||
| 11/18/2017 | Dickinson State | 24 | at | Southern Oregon | 55 | @ Front |