8/31/2017 | Wesley | 19 | at | Delaware Valley | 24 | | | NJAC |
| Stevenson | 7 | at | Frostburg State | 33 | | | @ NJAC |
| Moravian | 27 | at | King's | 30 | | | Cen |
9/1/2017 | Salisbury | 35 | at | Albright | 38 | OT | | NJAC |
| Fairleigh Dickinson-Florham | 38 | at | New Jersey | 24 | | | @ NJAC |
9/2/2017 | Franklin & Marshall | 48 | at | Lebanon Valley | 7 | | | Cen |
| Misericordia | 35 | at | Merchant Marine | 56 | | | @ NEWMAC |
| Wilkes | 19 | at | Muhlenberg | 62 | | | @ Cen |
| Widener | 0 | at | Rowan | 6 | | | @ NJAC |
| Lycoming | 6 | at | Susquehanna | 7 | | | @ Cen |
9/9/2017 | Delaware Valley | 34 | at | Lycoming | 3 | | | |
| Albright | 50 | at | Misericordia | 17 | | | |
| King's | 9 | at | Stevenson | 38 | | | |
| Fairleigh Dickinson-Florham | 7 | at | Widener | 49 | | | |
| Lebanon Valley | 36 | at | Wilkes | 0 | | | |
9/15/2017 | Delaware Valley | 34 | at | Wilkes | 14 | | | |
9/16/2017 | Stevenson | 52 | at | Fairleigh Dickinson-Florham | 14 | | | |
| King's | 44 | at | Lebanon Valley | 39 | | | |
| Albright | 21 | at | Lycoming | 17 | | | |
| Misericordia | 21 | at | Widener | 34 | | | |
9/23/2017 | Widener | 7 | at | Albright | 9 | | | |
| Stevenson | 7 | at | Delaware Valley | 27 | | | |
| Lycoming | 44 | at | King's | 41 | | | |
| Fairleigh Dickinson-Florham | 14 | at | Lebanon Valley | 24 | | | |
| Wilkes | 14 | at | Misericordia | 43 | | | |
9/29/2017 | Delaware Valley | 60 | at | Fairleigh Dickinson-Florham | 7 | | | |
9/30/2017 | Albright | 34 | at | King's | 31 | | | |
| Wilkes | 7 | at | Lycoming | 34 | | | |
| Misericordia | 7 | at | Stevenson | 65 | | | |
| Lebanon Valley | 20 | at | Widener | 28 | | | |
10/7/2017 | Delaware Valley | 41 | at | Albright | 6 | | | |
| Fairleigh Dickinson-Florham | 21 | at | Lycoming | 48 | | | |
| King's | 63 | at | Misericordia | 37 | | | |
| Widener | 30 | at | Wilkes | 7 | | | |
10/14/2017 | King's | 14 | at | Delaware Valley | 49 | | | |
| Stevenson | 24 | at | Lebanon Valley | 31 | | | |
| Lycoming | 17 | at | Widener | 31 | | | |
10/21/2017 | Wilkes | 31 | at | Fairleigh Dickinson-Florham | 49 | | | |
| Lebanon Valley | 17 | at | Misericordia | 0 | | | |
| Albright | 23 | at | Stevenson | 26 | | | |
10/28/2017 | Wilkes | 23 | at | Albright | 26 | | | |
| Lebanon Valley | 0 | at | Delaware Valley | 35 | | | |
| Fairleigh Dickinson-Florham | 15 | at | King's | 18 | | | |
| Misericordia | 17 | at | Lycoming | 35 | | | |
| Widener | 20 | at | Stevenson | 14 | | | |
11/3/2017 | Albright | 51 | at | Fairleigh Dickinson-Florham | 33 | | | |
11/4/2017 | Lycoming | 17 | at | Lebanon Valley | 20 | | | |
| Delaware Valley | 51 | at | Misericordia | 7 | | | |
| King's | 6 | at | Widener | 27 | | | |
| Stevenson | 44 | at | Wilkes | 12 | | | |
11/11/2017 | Lebanon Valley | 14 | at | Albright | 28 | | | |
| Widener | 13 | at | Delaware Valley | 47 | | | |
| Misericordia | 36 | at | Fairleigh Dickinson-Florham | 41 | | | |
| Wilkes | 26 | at | King's | 40 | | | |
| Lycoming | 14 | at | Stevenson | 20 | | | |
11/18/2017 | Susquehanna | 28 | at | Albright | 9 | | | Cen |
| Western New England | 0 | at | Delaware Valley | 35 | | | CCF |
| Widener | 7 | at | Franklin & Marshall | 21 | | | @ Cen |
11/19/2017 | Stevenson | 16 | vs | Alfred | 29 | | James Lynah Bowl (Newark DE) | vs E8 |
11/25/2017 | Husson | 15 | at | Delaware Valley | 37 | | D3 Playoff Round 2 | ECFC |
12/2/2017 | Brockport State | 31 | at | Delaware Valley | 28 | | D3 Playoff Quarterfinal | E8 |