| 9/2/2016 | Morrisville (1-9) | 0 | at | St Lawrence | 28 | E8 | ||
| 9/10/2016 | Norwich (5-5) | 0 | at | St Lawrence | 52 | ECFC | ||
| 9/17/2016 | St Lawrence | 38 | at | Endicott (5-5) | 0 | at NEF | ||
| 9/24/2016 | St Lawrence | 20 | at | Rensselaer (6-5,3-4) | 14 | |||
| 10/1/2016 | Springfield (5-5,4-3) | 14 | at | St Lawrence | 42 | |||
| 10/8/2016 | St Lawrence | 48 | at | Rochester (1-8,0-7) | 13 | |||
| 10/22/2016 | St Lawrence | 8 | at | Merchant Marine (5-4,4-3) | 0 | |||
| 10/29/2016 | Union NY (3-7,2-5) | 14 | at | St Lawrence | 26 | |||
| 11/5/2016 | Hobart (9-2,6-1) | 34 | at | St Lawrence | 18 | |||
| 11/12/2016 | St Lawrence | 28 | at | Worcester Polytechnic (6-4,3-4) | 21 |
| vs St Lawrence | vs Other Opponents | St Lawrence compared to OOs | |
| Record: | 1-9 | 45-45 | |
| Points Scored: | 11.00 | 26.14 | 15.14 |
| Points Allowed: | 30.80 | 25.21 | 5.59 |
| Margin: | -19.80 | 0.93 | 20.73 |
| Total Points: | 41.80 | 51.35 | -9.55 |