| 9/3/2016 | Plymouth State | 20 | at | Castleton State (4-6) | 7 | at ECFC | ||
| 9/10/2016 | Mount Ida (4-6) | 28 | at | Plymouth State | 30 | 3OT | ECFC | |
| 9/17/2016 | Plymouth State | 27 | at | Western Connecticut (5-5,4-4) | 19 | |||
| 9/24/2016 | UMass Dartmouth (5-5,4-4) | 14 | at | Plymouth State | 30 | |||
| 10/1/2016 | Plymouth State | 13 | at | Westfield State (2-8,1-7) | 14 | OT | ||
| 10/15/2016 | Plymouth State | 23 | at | Bridgewater State MA (8-3,8-0) | 29 | 2OT | ||
| 10/22/2016 | Framingham State (8-3,6-2) | 41 | at | Plymouth State | 7 | |||
| 10/29/2016 | Plymouth State | 10 | at | Worcester State (3-7,3-5) | 13 | |||
| 11/5/2016 | Massachusetts Maritime (4-6,3-5) | 7 | at | Plymouth State | 28 | |||
| 11/12/2016 | Fitchburg State (5-5,3-5) | 6 | at | Plymouth State | 23 |
| vs Plymouth State | vs Other Opponents | Plymouth State compared to OOs | |
| Record: | 4-6 | 44-48 | |
| Points Scored: | 17.80 | 23.00 | 5.20 |
| Points Allowed: | 21.10 | 25.45 | -4.35 |
| Margin: | -3.30 | -2.45 | 0.85 |
| Total Points: | 38.90 | 48.45 | -9.55 |