| 9/5/2015 | Carnegie Mellon (8-3) | 24 | at | Washington U | 45 | TPAC | ||
| 9/19/2015 | Washington U | 24 | at | Centre (8-2,6-2) | 34 | |||
| 9/26/2015 | Birmingham-Southern (5-5,3-5) | 13 | at | Washington U | 41 | |||
| 10/3/2015 | Washington U | 13 | at | Berry (7-3,6-2) | 20 | |||
| 10/10/2015 | Rhodes (4-6,2-6) | 7 | at | Washington U | 37 | |||
| 10/17/2015 | Washington U | 38 | at | Sewanee (1-9,0-8) | 14 | |||
| 10/24/2015 | Millsaps (3-7,2-6) | 32 | at | Washington U | 70 | |||
| 10/31/2015 | Washington U | 16 | at | Case Western Reserve (7-3) | 34 | at TPAC | ||
| 11/7/2015 | Washington U | 51 | at | Hendrix (8-3,7-1) | 54 | |||
| 11/14/2015 | Chicago (6-4,5-3) | 23 | at | Washington U | 37 |
| vs Washington U | vs Other Opponents | Washington U compared to OOs | |
| Record: | 4-6 | 53-39 | |
| Points Scored: | 25.50 | 28.42 | 2.92 |
| Points Allowed: | 37.20 | 23.78 | 13.42 |
| Margin: | -11.70 | 4.64 | 16.34 |
| Total Points: | 62.70 | 52.20 | 10.50 |