| 9/12/2015 | DePauw | 53 | at | Earlham (0-10) | 0 | at HCA | ||
| 9/19/2015 | Wooster (2-8,2-7) | 20 | at | DePauw | 49 | |||
| 9/26/2015 | DePauw | 45 | at | Hiram (4-6,4-5) | 7 | |||
| 10/3/2015 | DePauw | 38 | at | Kenyon (2-8,2-7) | 16 | |||
| 10/10/2015 | Wittenberg (8-2,7-2) | 30 | at | DePauw | 35 | |||
| 10/17/2015 | Allegheny (0-10,0-9) | 0 | at | DePauw | 50 | |||
| 10/24/2015 | DePauw | 22 | at | Ohio Wesleyan (5-5,5-4) | 27 | |||
| 10/31/2015 | DePauw | 31 | at | Denison (7-3,6-3) | 29 | |||
| 11/7/2015 | Oberlin (3-7,3-6) | 0 | at | DePauw | 53 | |||
| 11/14/2015 | Wabash (12-1,9-0) | 45 | at | DePauw | 17 |
| vs DePauw | vs Other Opponents | DePauw compared to OOs | |
| Record: | 2-8 | 41-52 | |
| Points Scored: | 17.40 | 25.25 | 7.85 |
| Points Allowed: | 39.30 | 30.03 | 9.27 |
| Margin: | -21.90 | -4.78 | 17.12 |
| Total Points: | 56.70 | 55.28 | 1.42 |