| 9/5/2015 | Buffalo State (7-3) | 29 | at | Otterbein | 0 | E8 | ||
| 9/19/2015 | Otterbein | 31 | at | Marietta (2-8,2-7) | 21 | |||
| 9/26/2015 | Wilmington (1-9,0-9) | 9 | at | Otterbein | 31 | |||
| 10/3/2015 | Otterbein | 31 | at | Heidelberg (5-5,5-4) | 49 | |||
| 10/10/2015 | Otterbein | 49 | at | Capital (3-7,3-6) | 34 | |||
| 10/17/2015 | Muskingum (1-9,1-8) | 21 | at | Otterbein | 28 | |||
| 10/24/2015 | Baldwin-Wallace (7-3,7-2) | 55 | at | Otterbein | 21 | |||
| 10/31/2015 | Otterbein | 0 | at | Mount Union (15-0,9-0) | 55 | |||
| 11/7/2015 | John Carroll (8-2,7-2) | 42 | at | Otterbein | 13 | |||
| 11/14/2015 | Otterbein | 10 | at | Ohio Northern (9-3,7-2) | 42 |
| vs Otterbein | vs Other Opponents | Otterbein compared to OOs | |
| Record: | 6-4 | 52-45 | |
| Points Scored: | 35.70 | 30.21 | -5.49 |
| Points Allowed: | 21.40 | 27.96 | -6.56 |
| Margin: | 14.30 | 2.25 | -12.05 |
| Total Points: | 57.10 | 58.17 | -1.07 |