| 9/5/2015 | Knox | 21 | at | Eureka (5-5) | 32 | at UMWAC | ||
| 9/12/2015 | Carleton (1-9) | 20 | at | Knox | 23 | MIA | ||
| 9/26/2015 | Knox | 20 | at | Lawrence (1-9,0-8) | 6 | |||
| 10/3/2015 | Macalester (4-6,4-4) | 46 | at | Knox | 19 | |||
| 10/10/2015 | Knox | 3 | at | Lake Forest (4-6,4-4) | 34 | |||
| 10/17/2015 | Cornell IA (5-5,4-4) | 38 | at | Knox | 16 | |||
| 10/24/2015 | Knox | 26 | at | Grinnell (2-8,2-7) | 12 | |||
| 10/31/2015 | Knox | 13 | at | Illinois College (5-5,4-4) | 59 | |||
| 11/7/2015 | Monmouth IL (8-2,7-1) | 49 | at | Knox | 7 | |||
| 11/14/2015 | Knox | 21 | at | Beloit (3-7,3-6) | 24 |
| vs Knox | vs Other Opponents | Knox compared to OOs | |
| Record: | 7-3 | 31-59 | |
| Points Scored: | 32.00 | 24.59 | -7.41 |
| Points Allowed: | 16.90 | 32.02 | -15.12 |
| Margin: | 15.10 | -7.43 | -22.53 |
| Total Points: | 48.90 | 56.61 | -7.71 |