| 9/5/2015 | Prairie View (8-2,8-1) | 38 | at | Texas Southern | 11 | |||
| 9/11/2015 | Bacone (2-9) | 0 | at | Texas Southern | 63 | CSFL (NAIA) | ||
| 9/19/2015 | Texas Southern | 24 | at | Ark Pine Bluff (2-9,1-8) | 20 | |||
| 9/26/2015 | Texas Southern | 30 | at | Jackson State (3-8,3-6) | 34 | |||
| 10/1/2015 | Alabama State (6-5,5-4) | 41 | at | Texas Southern | 23 | |||
| 10/17/2015 | Texas Southern | 49 | at | Mississippi Valley State (0-11,0-9) | 21 | |||
| 10/24/2015 | Southern (6-5,6-3) | 40 | at | Texas Southern | 21 | |||
| 11/7/2015 | Texas Southern | 15 | at | Grambling (9-3,9-1) | 41 | |||
| 11/14/2015 | Alcorn State (9-4,8-2) | 65 | at | Texas Southern | 13 | |||
| 11/28/2015 | Texas Southern | 7 | at | Alabama A&M (4-7,4-5) | 38 |
| vs Texas Southern | vs Other Opponents | Texas Southern compared to OOs | |
| Record: | 7-3 | 42-60 | |
| Points Scored: | 33.80 | 27.35 | -6.45 |
| Points Allowed: | 25.60 | 35.23 | -9.63 |
| Margin: | 8.20 | -7.88 | -16.08 |
| Total Points: | 59.40 | 62.58 | -3.18 |