| 8/31/2013 | Coastal Carolina (12-3) | 27 | at | South Carolina State | 20 | BIGS | ||
| 9/7/2013 | South Carolina State | 13 | at | Clemson (11-2) | 52 | at ACC | ||
| 9/14/2013 | Alabama A&M (4-8) | 0 | at | South Carolina State | 32 | SWAC | ||
| 9/21/2013 | South Carolina State | 59 | at | Benedict (4-6) | 6 | at SIAC | ||
| 9/28/2013 | Hampton (4-8,4-4) | 6 | at | South Carolina State | 30 | |||
| 10/5/2013 | North Carolina A&T (7-4,4-4) | 24 | vs | South Carolina State | 29 | Atlanta GA | ||
| 10/10/2013 | South Carolina State | 44 | at | North Carolina Central (5-7,3-5) | 3 | |||
| 10/26/2013 | South Carolina State | 3 | at | Bethune-Cookman (10-3,7-1) | 14 | |||
| 11/2/2013 | South Carolina State | 45 | at | Savannah State (1-11,0-8) | 9 | |||
| 11/9/2013 | Florida A&M (3-9,2-6) | 21 | at | South Carolina State | 25 | |||
| 11/14/2013 | Morgan State (5-7,5-3) | 3 | at | South Carolina State | 38 | |||
| 11/23/2013 | South Carolina State | 17 | at | Norfolk State (3-9,3-5) | 3 | |||
| 11/30/2013 | Furman (8-6) | 30 | at | South Carolina State | 20 | FCS Round 1 | SOCON |
| vs South Carolina State | vs Other Opponents | South Carolina State compared to OOs | |
| Record: | 4-9 | 73-74 | |
| Points Scored: | 15.23 | 24.63 | 9.40 |
| Points Allowed: | 28.85 | 26.70 | 2.15 |
| Margin: | -13.62 | -2.07 | 11.55 |
| Total Points: | 44.08 | 51.33 | -7.25 |