| 9/1/2012 | Northwestern State | 6 | at | Texas Tech (8-5) | 44 | at B12 | ||
| 9/8/2012 | Arkansas-Monticello (0-10) | 24 | at | Northwestern State | 31 | GAC (D2) | ||
| 9/15/2012 | Northwestern State | 34 | at | Nevada (7-6) | 45 | at MW | ||
| 9/22/2012 | Mississippi Valley State (5-6) | 14 | at | Northwestern State | 45 | SWAC | ||
| 9/29/2012 | Northwestern State | 22 | at | McNeese State (7-4,4-3) | 30 | |||
| 10/6/2012 | Lamar (4-8,1-6) | 23 | at | Northwestern State | 30 | |||
| 10/13/2012 | Northwestern State | 22 | at | Southeastern Louisiana (5-6,5-2) | 27 | |||
| 10/27/2012 | Nicholls State (1-10,0-7) | 26 | at | Northwestern State | 27 | |||
| 11/3/2012 | Northwestern State | 14 | at | Central Arkansas (9-3,6-1) | 35 | |||
| 11/10/2012 | Sam Houston (11-4,6-1) | 52 | at | Northwestern State | 17 | |||
| 11/17/2012 | Northwestern State | 17 | at | Stephen F. Austin (5-6,4-3) | 34 |
| vs Northwestern State | vs Other Opponents | Northwestern State compared to OOs | |
| Record: | 7-4 | 55-64 | |
| Points Scored: | 32.18 | 28.45 | -3.73 |
| Points Allowed: | 24.09 | 29.94 | -5.85 |
| Margin: | 8.09 | -1.49 | -9.58 |
| Total Points: | 56.27 | 58.39 | -2.12 |