| 9/3/2011 | Buffalo Bulls 16 @ Pittsburgh 35 | |
| 9/10/2011 | Maine Black Bears 29 @ Pittsburgh 35 | |
| 9/17/2011 | Pittsburgh 27 @ Iowa Hawkeyes 31 | |
| 9/24/2011 | Notre Dame Fighting Irish 15 @ Pittsburgh 12 | |
| 9/29/2011 | South Florida Bulls 17 @ Pittsburgh 44 | † |
| 10/8/2011 | Pittsburgh 10 @ Rutgers Scarlet Knights 34 | † |
| 10/15/2011 | Utah Utes 26 @ Pittsburgh 14 | |
| 10/26/2011 | Connecticut Huskies 20 @ Pittsburgh 35 | † |
| 11/5/2011 | Cincinnati Bearcats 26 @ Pittsburgh 23 | † |
| 11/12/2011 | Pittsburgh 21 @ Louisville Cardinals 14 | † |
| 11/25/2011 | Pittsburgh 20 @ West Virginia Mountaineers 21 | † |
| 12/3/2011 | Syracuse Orangemen 20 @ Pittsburgh 33 | † |
| 1/7/2012 | SMU Mustangs 28 vs Pittsburgh 6 ( BBVA Compass Bowl ) |