| 9/3/2011 | Northeastern State Riverhawks 3 @ Texas-San Antonio 21 | |
| 9/10/2011 | McMurry 24 @ Texas-San Antonio 21 | |
| 9/17/2011 | Texas-San Antonio 22 @ Southern Utah Thunderbirds 45 | |
| 9/24/2011 | Bacone Warriors 7 @ Texas-San Antonio 54 | |
| 10/1/2011 | Texas-San Antonio 7 @ Sam Houston Bearkats 22 | |
| 10/8/2011 | South Alabama Jaguars 30 @ Texas-San Antonio 27 3OT | † |
| 10/15/2011 | Texas-San Antonio 17 @ UC Davis Aggies 38 | |
| 10/29/2011 | Georgia State Panthers 14 @ Texas-San Antonio 17 1OT | † |
| 11/12/2011 | Texas-San Antonio 21 @ McNeese State Cowboys 24 | |
| 11/19/2011 | Minot State Beavers 7 @ Texas-San Antonio 49 |