| 9/3/2011 | Miami-Ohio | 6 | at | Missouri | 17 | ||||
| 9/9/2011 | Missouri | 30 | at | Arizona State | 37 | OT | |||
| 9/17/2011 | Western Illinois 1AA | 0 | at | Missouri | 69 | ||||
| 9/24/2011 | Missouri | 28 | at | Oklahoma | 38 | B12 | |||
| 10/8/2011 | Missouri | 17 | at | Kansas State | 24 | B12 | |||
| 10/15/2011 | Iowa State | 17 | at | Missouri | 52 | B12 | |||
| 10/22/2011 | Oklahoma State | 45 | at | Missouri | 24 | B12 | |||
| 10/29/2011 | Missouri | 38 | at | Texas A&M | 31 | OT | B12 | ||
| 11/5/2011 | Missouri | 39 | at | Baylor | 42 | B12 | |||
| 11/12/2011 | Texas | 5 | at | Missouri | 17 | B12 | |||
| 11/19/2011 | Texas Tech | 27 | at | Missouri | 31 | B12 | |||
| 11/26/2011 | Missouri | 24 | vs | Kansas | 10 | B12 | Kansas City MO | ||
| 12/26/2011 | North Carolina | 24 | vs | Missouri | 41 | Independence Bowl |