| 9/3/2011 | UCLA | 34 | at | Houston | 38 | ||||
| 9/10/2011 | Houston | 48 | at | North Texas | 23 | ||||
| 9/17/2011 | Houston | 35 | at | Louisiana Tech | 34 | ||||
| 9/24/2011 | Georgia State 1AA | 0 | at | Houston | 56 | ||||
| 9/29/2011 | Houston | 49 | at | UTEP | 42 | CUSA | |||
| 10/8/2011 | East Carolina | 3 | at | Houston | 56 | CUSA | |||
| 10/22/2011 | Marshall | 28 | at | Houston | 63 | CUSA | |||
| 10/27/2011 | Rice | 34 | at | Houston | 73 | CUSA | |||
| 11/5/2011 | Houston | 56 | at | UAB | 13 | CUSA | |||
| 11/10/2011 | Houston | 73 | at | Tulane | 17 | CUSA | |||
| 11/19/2011 | SMU | 7 | at | Houston | 37 | CUSA | |||
| 11/25/2011 | Houston | 48 | at | Tulsa | 16 | CUSA | |||
| 12/3/2011 | Southern Miss | 49 | at | Houston | 28 | CUSA | CUSA | ||
| 1/2/2012 | Houston | 30 | vs | Penn State | 14 | TicketCity Bowl |