| 9/11/2010 | Pacific Lutheran Lutes 27 @ Hamline 20 | |
| 9/18/2010 | Hamline 38 @ Augsburg Auggies 42 | † |
| 9/25/2010 | Carleton Knights 45 @ Hamline 21 | † |
| 10/2/2010 | Macalester Scots 30 @ Hamline 49 | |
| 10/9/2010 | Hamline 14 @ Gustavus Adolphus Golden Gusties 42 | † |
| 10/16/2010 | St Thomas Tommies 61 @ Hamline 17 | † |
| 10/23/2010 | Hamline 3 @ Concordia-Moorhead Cobbers 30 | † |
| 10/30/2010 | St Olaf Oles 42 @ Hamline 10 | † |
| 11/6/2010 | Bethel MN Royals 45 @ Hamline 0 | † |
| 11/13/2010 | Hamline 0 @ St John's MN Johnnies 49 | † |