| 9/4/2010 | Miami-Ohio Redhawks 12 @ Florida 34 | |
| 9/11/2010 | South Florida Bulls 14 @ Florida 38 | |
| 9/18/2010 | Florida 31 @ Tennessee Volunteers 17 | † |
| 9/25/2010 | Kentucky Wildcats 14 @ Florida 48 | † |
| 10/2/2010 | Florida 6 @ Alabama Crimson Tide 31 | † |
| 10/9/2010 | LSU Tigers 33 @ Florida 29 | † |
| 10/16/2010 | Mississippi State Bulldogs 10 @ Florida 7 | † |
| 10/30/2010 | Georgia Bulldogs 31 vs Florida 34 1OT (Jacksonville FL) | † |
| 11/6/2010 | Florida 55 @ Vanderbilt Commodores 14 | † |
| 11/13/2010 | South Carolina Gamecocks 36 @ Florida 14 | † |
| 11/20/2010 | Appalachian State Mountaineers 10 @ Florida 48 | |
| 11/27/2010 | Florida 7 @ Florida State Seminoles 31 | |
| 1/1/2011 | Florida 37 vs Penn State Nittany Lions 24 (Tampa - Outback Bowl) |