| 8/27/2009 Quincy (NAIA) 26 at Indiana St (1AA) 20 OT |
| 8/29/2009 Johnson C Smith (D2) 39 at West Virginia Tech (NAIA) 49 |
| 9/3/2009 Oregon 8 at Boise St 19 |
| 9/3/2009 Anderson (D3) 16 at Taylor (NAIA) 31 |
| 9/3/2009 Villanova (1AA) 27 at Temple 24 |
| 9/5/2009 Arkansas-Monticello (D2) 27 at Ark Pine Bluff (1AA) 3 |
| 9/5/2009 Shaw (D2) 21 at Bethune-Cookman (1AA) 6 |
| 9/5/2009 Richmond (1AA) 24 at Duke 16 |
| 9/5/2009 Langston (NAIA) 31 at Lincoln MO (D2) 6 |
| 9/5/2009 Apprentice (D3) 19 at Malone (NAIA) 35 |
| 9/5/2009 Concordia-St Paul (D2) 21 at Minot St (NAIA) 24 |
| 9/5/2009 Colorado St-Pueblo (D2) 28 at NW Oklahoma St (NAIA) 34 |
| 9/5/2009 Seton Hill (D2) 21 at Ohio Dominican (NAIA) 44 |
| 9/5/2009 BYU 14 vs Oklahoma 13 |
| 9/5/2009 Pace (D2) 14 at Salisbury (D3) 34 |
| 9/5/2009 Valparaiso (1AA) 6 at St Joseph's (D2) 31 |
| 9/5/2009 William & Mary (1AA) 26 at Virginia 14 |
| 9/5/2009 Stonehill (D2) 45 at Wagner (1AA) 42 |
| 9/5/2009 Lambuth (NAIA) 27 at West Georgia (D2) 20 |
| 9/6/2009 Colorado St 23 at Colorado 17 |
| 9/11/2009 Colorado 38 at Toledo 54 |
| 9/12/2009 New Hampshire (1AA) 23 at Ball State 16 |
| 9/12/2009 Campbell (1AA) 28 at Birmingham-Southern (D3) 35 OT |
| 9/12/2009 Lenoir-Rhyne (D2) 42 at Davidson (1AA) 0 |
| 9/12/2009 Urbana (D2) 13 at Dayton (1AA) 10 |
| 9/12/2009 Johnson C Smith (D2) 27 vs Edward Waters (NAIA) 41 |
| 9/12/2009 Kansas St 15 at UL Lafayette 17 |
| 9/12/2009 Central Michigan 29 at Michigan St 27 |
| 9/12/2009 Cumberlands KY (NAIA) 55 at Mississippi College (D3) 26 |
| 9/12/2009 Wesley (D3) 28 at North Greenville (D2) 3 |
| 9/12/2009 Houston 45 at Oklahoma St 35 |
| 9/12/2009 LaGrange (D3) 19 at Shorter (NAIA) 42 |
| 9/12/2009 TCU 30 at Virginia 14 |
| 9/12/2009 Apprentice (D3) 0 at Virginia-Wise (NAIA) 48 |
| 9/12/2009 Hawaii 38 vs Washington St 20 |
| 9/19/2009 Haskell (NAIA) 25 at MacMurray (D3) 22 |
| 9/19/2009 Middle Tenn St 32 at Maryland 31 |
| 9/19/2009 UW-Stevens Point (D3) 21 at Missouri S&T (D2) 17 |
| 9/19/2009 Langston (NAIA) 27 vs Panhandle St (D2) 21 |
| 9/19/2009 Northern Illinois 28 at Purdue 21 |
| 9/19/2009 Virginia 34 at Southern Miss 37 |
| 9/19/2009 Central Arkansas (1AA) 28 at Western Kentucky 7 |
| 9/26/2009 Malone (NAIA) 65 at Anna Maria (D3) 10 |
| 9/26/2009 UW-Stevens Point (D3) 7 at Azusa Pacific (NAIA) 23 |
| 9/26/2009 MacMurray (D3) 34 at Bethany KS (NAIA) 63 |
| 9/26/2009 TCU 14 at Clemson 10 |
| 9/26/2009 Savannah St (1AA) 21 at Concordia AL (NAIA) 23 |
| 9/26/2009 Texas Tech 28 at Houston 29 |
| 9/26/2009 Central Washington (D2) 33 at Idaho St (1AA) 22 |
| 9/26/2009 Incarnate Word (D2) 14 at Langston (NAIA) 17 |
| 9/26/2009 Albright (D3) 26 at Pace (D2) 20 |
| 9/26/2009 Panhandle St (D2) 50 at SW Assem of God (NAIA) 58 |
| 9/26/2009 Walsh (NAIA) 59 at Urbana (D2) 21 |
| 9/26/2009 Louisville 14 at Utah 30 |
| 9/26/2009 Missouri S&T (D2) 0 at UW-La Crosse (D3) 48 |
| 9/26/2009 Ohio Dominican (NAIA) 31 at UW-Oshkosh (D3) 29 |
| 9/26/2009 Carthage (D3) 40 at Valparaiso (1AA) 24 |
| 10/3/2009 Ohio Dominican (NAIA) 52 at Lake Erie (D2) 49 |
| 10/3/2009 LaGrange (D3) 20 at Lincoln MO (D2) 7 |
| 10/3/2009 Lambuth (NAIA) 58 at West Alabama (D2) 40 |
| 10/10/2009 Vanderbilt 13 at Army 16 OT |
| 10/10/2009 Peru St (NAIA) 16 at Lincoln MO (D2) 14 |
| 10/10/2009 Houston 31 at Mississippi St 24 |
| 10/10/2009 St Joseph's (D2) 14 at Ohio Dominican (NAIA) 45 |
| 10/17/2009 Grand View (NAIA) 24 at Kentucky Wesleyan (D2) 12 |
| 10/17/2009 Sioux Falls (NAIA) 28 at North Dakota (1AA) 13 |
| 10/24/2009 Marian IN (NAIA) 28 at Albion (D3) 10 |
| 10/24/2009 Wake Forest 10 at Navy 13 |
| 10/24/2009 Central St (D2) 35 at Ohio Dominican (NAIA) 55 |
| 10/31/2009 Azusa Pacific (NAIA) 55 at Trinity TX (D3) 27 |
| 10/31/2009 Ohio Dominican (NAIA) 21 at Urbana (D2) 12 |
| 10/31/2009 Apprentice (D3) 14 at Webber Int'l (NAIA) 17 |
| 11/7/2009 Ohio Dominican (NAIA) 42 at New Haven (D2) 13 |
| 11/7/2009 Navy 23 at Notre Dame 21 |
| 11/7/2009 Panhandle St (D2) 20 at Southern Nazarene (NAIA) 48 |
| 11/7/2009 Lake Erie (D2) 13 at Wesley (D3) 28 |
| 11/14/2009 Southern Virginia (NAIA) 14 at Apprentice (D3) 10 |
| 11/14/2009 NW Oklahoma St (NAIA) 68 at Panhandle St (D2) 28 |
| 11/14/2009 Webber Int'l (NAIA) 35 at Savannah St (1AA) 20 |
| 11/26/2009 Tuskegee (D2) 21 at Alabama St (1AA) 0 |
| 12/5/2009 Fresno St 53 at Illinois 52 |
| 12/22/2009 Oregon St 20 vs BYU 44 |
| 12/23/2009 Utah 37 vs California 27 |
| 12/31/2009 Missouri 13 vs Navy 35 |