| 9/5/2009 | Stony Brook 10 @ Hofstra 17 | |
| 9/12/2009 | Hofstra 40 @ Bryant 24 | |
| 9/19/2009 | Hofstra 0 @ Richmond 47 | † |
| 9/26/2009 | Hofstra 10 @ Western Michigan 24 | |
| 10/3/2009 | James Madison 17 @ Hofstra 24 | † |
| 10/10/2009 | Maine 16 @ Hofstra 14 | † |
| 10/17/2009 | Hofstra 28 @ Rhode Island 16 | † |
| 10/24/2009 | New Hampshire 18 @ Hofstra 10 | † |
| 11/7/2009 | Hofstra 24 @ Delaware 28 | † |
| 11/14/2009 | Hofstra 14 @ Northeastern 13 | † |
| 11/21/2009 | Massachusetts 38 @ Hofstra 52 | † |