| 9/5/2009 | Prairie View | 17 | @ | Texas Southern | 7 | SWAC | |||
| 9/12/2009 | Texas Southern | 0 | @ | UL Monroe | 58 | ||||
| 9/19/2009 | Texas College NAIA | 6 | @ | Texas Southern | 75 | ||||
| 9/26/2009 | Texas Southern | 18 | @ | Texas St | 52 | ||||
| 10/10/2009 | Texas Southern | 0 | @ | Rutgers | 42 | ||||
| 10/17/2009 | Texas Southern | 19 | @ | Jackson St | 17 | SWAC | |||
| 10/31/2009 | Alcorn St | 21 | @ | Texas Southern | 51 | SWAC | |||
| 11/7/2009 | Texas Southern | 30 | @ | MS Valley St | 7 | SWAC | |||
| 11/12/2009 | Texas Southern | 33 | @ | Grambling | 47 | SWAC | |||
| 11/28/2009 | Texas Southern | 14 | vs | Ark Pine Bluff | 10 | SWAC | Dallas TX | ||
| 12/5/2009 | Southern Univ | 25 | @ | Texas Southern | 30 | SWAC |