| 8/30/2008 | Villanova | 21 | @ | West Virginia | 48 | ||||
| 9/13/2008 | Lehigh | 14 | @ | Villanova | 33 | ||||
| 9/20/2008 | Villanova | 20 | @ | Penn | 14 | OT | |||
| 9/27/2008 | Richmond | 20 | @ | Villanova | 26 | CAAF | |||
| 10/4/2008 | Villanova | 38 | @ | William & Mary | 28 | CAAF | |||
| 10/18/2008 | Villanova | 44 | @ | Rhode Island | 7 | CAAF | |||
| 10/25/2008 | James Madison | 23 | @ | Villanova | 19 | CAAF | |||
| 11/1/2008 | Villanova | 20 | @ | Northeastern | 14 | CAAF | |||
| 11/8/2008 | New Hampshire | 13 | @ | Villanova | 24 | CAAF | |||
| 11/15/2008 | Towson | 31 | @ | Villanova | 34 | CAAF | |||
| 11/22/2008 | Villanova | 21 | @ | Delaware | 7 | CAAF | |||
| 11/29/2008 | Colgate | 28 | @ | Villanova | 55 | FCS championship round 1 | |||
| 12/6/2008 | Villanova | 27 | @ | James Madison | 31 | CAAF | FCS quarterfinals |