| 9/1/2007 | NC A&T | 7 | @ | Winston-Salem St | 28 | MEAC | |||
| 9/8/2007 | Winston-Salem St | 21 | @ | Coastal Car | 28 | ||||
| 9/15/2007 | Winston-Salem St | 19 | @ | Morgan St | 17 | MEAC | |||
| 9/22/2007 | Winston-Salem St | 7 | @ | S Carolina St | 20 | MEAC | |||
| 9/29/2007 | Winston-Salem St | 24 | @ | Howard | 21 | OT | MEAC | ||
| 10/6/2007 | Florida A&M | 23 | vs | Winston-Salem St | 27 | MEAC | Indianapolis IN | ||
| 10/20/2007 | Winston-Salem St | 14 | @ | Bethune-Cookman | 9 | MEAC | |||
| 10/27/2007 | Hampton | 19 | @ | Winston-Salem St | 20 | MEAC | |||
| 11/3/2007 | Delaware St | 23 | @ | Winston-Salem St | 20 | MEAC | |||
| 11/10/2007 | North Carolina Central | 10 | @ | Winston-Salem St | 35 | ||||
| 11/17/2007 | Winston-Salem St | 20 | @ | Norfolk St | 23 | MEAC |