| 9/3/2005 | Central Conn | 24 | @ | Colgate | 22 | ||||
| 9/10/2005 | Massachusetts | 14 | @ | Colgate | 17 | ||||
| 9/17/2005 | Colgate | 21 | @ | Dartmouth | 26 | ||||
| 10/1/2005 | Cornell | 20 | @ | Colgate | 34 | ||||
| 10/8/2005 | Colgate | 16 | @ | Princeton | 10 | ||||
| 10/15/2005 | Fordham | 0 | @ | Colgate | 23 | Pat | |||
| 10/22/2005 | Colgate | 27 | @ | Holy Cross | 14 | Pat | |||
| 10/29/2005 | Lehigh | 50 | @ | Colgate | 34 | Pat | |||
| 11/5/2005 | Colgate | 18 | @ | Lafayette | 15 | Pat | |||
| 11/12/2005 | Bucknell | 10 | @ | Colgate | 16 | Pat | |||
| 11/19/2005 | Colgate | 34 | @ | Georgetown | 7 | Pat |